89283-46-5 Usage
Uses
Used in Organic Synthesis:
4-chloro-6-(methylsulfonyl)pyrimidine is used as a building block in organic synthesis for the creation of complex organic molecules. Its unique structure allows for the formation of various chemical bonds and reactions, facilitating the synthesis of a wide range of compounds.
Used in Pharmaceutical Production:
As an intermediate in the production of pharmaceuticals, 4-chloro-6-(methylsulfonyl)pyrimidine plays a crucial role in the synthesis of various drugs. Its presence in the molecular structure of these drugs contributes to their therapeutic properties and effectiveness in treating different medical conditions.
Used in Agrochemical Manufacturing:
4-chloro-6-(methylsulfonyl)pyrimidine is also utilized in the manufacture of agrochemicals, such as pesticides and herbicides. Its incorporation into these products enhances their efficacy in controlling pests and weeds, thereby improving crop yields and protecting agricultural resources.
Used in Dye and Pigment Industries:
In the dye and pigment industries, 4-chloro-6-(methylsulfonyl)pyrimidine is employed as a key component in the production of various dyes, pigments, and other specialty chemicals. Its chemical properties enable the creation of a diverse range of colors and shades, catering to the needs of different industries, such as textiles, plastics, and printing.
Overall, 4-chloro-6-(methylsulfonyl)pyrimidine is a valuable chemical compound with diverse applications across multiple industries, including organic synthesis, pharmaceuticals, agrochemicals, and the dye and pigment sectors. Its unique structure and properties make it an essential component in the development and production of various products.
Check Digit Verification of cas no
The CAS Registry Mumber 89283-46-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,8 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 89283-46:
(7*8)+(6*9)+(5*2)+(4*8)+(3*3)+(2*4)+(1*6)=175
175 % 10 = 5
So 89283-46-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2O2S/c1-11(9,10)5-2-4(6)7-3-8-5/h2-3H,1H3
89283-46-5Relevant academic research and scientific papers
HETEROCYCLIC AMIDES AS RIP1 KINASE INHIBITORS
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, (2019/12/15)
Disclosed are compounds having the formula: (I) wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
Synthesis of Alkylated Pyrimidines via Photoinduced Coupling Using Benzophenone as a Mediator
Kamijo, Shin,Kamijo, Kaori,Murafuji, Toshihiro
, p. 2664 - 2671 (2017/03/14)
The synthesis of alkylated pyrimidines was achieved via benzophenone-mediated photoinduced coupling between saturated heterocycles and sulfonylpyrimidines. The pyrimidine ring was selectively introduced at the nonacidic C(sp3)-H bond proximal to heteroatoms including oxygen, nitrogen, and sulfur. This is a coupling reaction mediated solely by photoexcited benzophenone, an organic molecule, without the aid of any metallic catalysts or reagents.
Chemoselective reactions of 4,6-dichloro-2-(methylsulfonyl)pyrimidine and related electrophiles with amines
Baiazitov, Ramil,Du, Wu,Lee, Chang-Sun,Hwang, Seongwoo,Almstead, Neil G.,Moon, Young-Choon
, p. 1764 - 1784 (2013/07/26)
Chemoselective SNAr reactions of 4,6-dichloro-2-(methylsulfonyl) pyrimidine and several related electrophiles with amines and their derivatives are described. In the presence of weak bases anilines and secondary aliphatic amines selectively displace the chloride group. Deprotonated anilines and their carbonyl derivatives displace the sulfone group. Sterically and electronically unbiased primary aliphatic amines selectively displace the sulfone group in 4,6-dichloro-2-(methylsulfonyl)pyrimidine; however, their reactions with other electrophiles generally are less selective. Steric-driven selectivity explanation was proposed. Georg Thieme Verlag Stuttgart. New York.
