89284-20-8

Usage

Uses

Used in Pharmaceutical Industry:
3-CHLORO-4-HYDROXYPYRIDINE is used as a chemical intermediate for the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 3-CHLORO-4-HYDROXYPYRIDINE is used as a building block for the production of fungicides and herbicides. Its incorporation into these products contributes to their effectiveness in controlling pests and diseases in agriculture.
As a potentially hazardous chemical, 3-CHLORO-4-HYDROXYPYRIDINE requires careful handling and adherence to proper safety protocols to minimize risks during its use in various applications.

InChI:InChI=1/C5H4ClNO/c6-4-3-7-2-1-5(4)8/h1-3H,(H,7,8)

Upstream product

• 626-64-2 pyridin-4-ol 

Downstream Products

• 1357589-07-1 3-(1-phenyl-1H-pyrazol-5-yl)-1-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one 
• 1357589-10-6 3-chloro-1-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one 
• 89379-79-3 3-Chlor-4-methoxy-pyridin 

Relevant academic research and scientific papers

Preparation method of pyridine derivative (by machine translation)

To the method, piperidine-4-one hydrochloride is used as a raw material, and a series of pyridine derivatives are obtained through halogenation reaction and elimination reaction. The reaction is eliminated by reacting piperidine-4-one hydrochloride with a specific amount of the 3,5 - halogenating agent in a halogenation 3, 3, 5 - reaction with a halogen-3, 3, 5, 5 - based reaction, followed by reaction with a pyridine derivative of a hydroxyl group, an amino group 4 - or a dimethylamino group, respectively, by eliminating the reaction with a different kind of basic agent. The method is simple and convenient to operate, mild in condition, short in technological process, low in waste water yield, environment-friendly, low in cost and beneficial to green industrial production of the pyridine derivative. (by machine translation)

Convenient chlorination of some special aromatic compounds using N-chlorosuccinimide

Some chlorinated aromatic compounds, including indole, benzofuran, carbazole, pyridine and aniline derivatives, are difficult to obtain through convenient chlorination. We herein report their efficient synthesis through chlorination with N-chlorosuccinimide (NCS). Optimization of the reaction conditions, including the temperature and the choice of solvent, was also investigated. This approach, which is characterized by a facile procedure, comparatively high yields and environmentally friendly features, provides a straightforward and inexpensive route to several chlorinated aromatic compounds. Georg Thieme Verlag Stuttgart · New York.