892859-23-3

Upstream product

• 892859-22-2 C₄₁H₇₂O₁₀Si₃ 
• 591-51-5 phenyllithium 
• 237762-05-9 7-TES-2-debenzoylbaccatin-1,2-carbonate 
• 892859-18-6 C₄₁H₇₄O₁₁Si₃ 
• 892859-30-2 C₃₉H₇₂O₁₀Si₃ 
• 892859-20-0 C₃₉H₇₁IO₉Si₃ 
• 892859-21-1 C₃₉H₇₂O₉Si₃ 
• 892859-31-3 C₃₉H₇₀O₉Si₃ 
• 892859-19-7 C₃₉H₇₀O₉Si₃ 

Downstream Products

• 892859-28-8 2-(4-methoxy-phenyl)-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-(4,10-diacetoxy-2-benzoyloxy-1-hydroxy-4,8,12,15,15-pentamethyl-5,9-dioxo-7-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-13-yl) ester 
• 892859-34-6 (2R,4S,5R)-2-(4-Methoxy-phenyl)-4-phenyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-((1S,2S,3R,4R,7S,8S,10R,13S)-4,10-diacetoxy-2-benzoyloxy-1,7-dihydroxy-4,8,12,15,15-pentamethyl-5,9-dioxo-tricyclo[9.3.1.0^3,8]pentadec-11-en-13-yl) ester 
• 892859-27-7 Benzoic acid (1S,2S,3R,4R,7S,8S,10R,13S)-4,10-diacetoxy-1,13-dihydroxy-4,8,12,15,15-pentamethyl-5,9-dioxo-7-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester 
• 892859-32-4 Benzoic acid (1S,2S,3R,4R,7S,8S,10R,13S)-4-acetoxy-1,10,13-trihydroxy-4,8,12,15,15-pentamethyl-5,9-dioxo-7-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester 
• 892859-33-5 Benzoic acid (1S,2S,3R,4R,7S,8S,10R,13S)-4,10-diacetoxy-1,7,13-trihydroxy-4,8,12,15,15-pentamethyl-5,9-dioxo-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester 
• 892859-25-5 Benzoic acid (1S,2S,3R,4R,7S,8S,10R,13S)-4-acetoxy-1,7,10,13-tetrahydroxy-4,8,12,15,15-pentamethyl-5,9-dioxo-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester 

Relevant academic research and scientific papers

Semisynthesis and biological evaluation of a novel D-seco docetaxel analogue

A 4-methyl-5-oxo docetaxel analogue has been prepared starting from 10-deacetylbaccatin III. This new D-seco docetaxel analogue is slightly less potent than docetaxel at microtubule stabilization in vitro and has about 1/1000th the cytotoxicity of docetax