892861-37-9Relevant articles and documents
Discovery of a new chemical lead for a matrix metalloproteinase inhibitor
Ikura, Masahiro,Nakatani, Shingo,Yamamoto, Shingo,Habashita, Hiromu,Sugiura, Tsuneyuki,Takahashi, Kanji,Ogawa, Koji,Ohno, Hiroyuki,Nakai, Hisao,Toda, Masaaki
, p. 4241 - 4252 (2007/10/03)
A series of N-benzoyl γ-aminobutyric hydroxamic acids were synthesized and evaluated as matrix metalloproteinase inhibitors. First, we focused on chemical modification of the N-benzoyl residue. Introduction of electron-rich para-substituents was effective