89305-77-1Relevant academic research and scientific papers
New Atglistatin closely related analogues: Synthesis and structure-activity relationship towards adipose triglyceride lipase inhibition
Roy, Pierre-Philippe,D'Souza, Kenneth,Cuperlovic-Culf, Miroslava,Kienesberger, Petra C.,Touaibia, Mohamed
, p. 290 - 298 (2016)
Adipose Triglyceride Lipase (ATGL) performs the first and rate-limiting step in lipolysis by hydrolyzing triacylglycerols stored in lipid droplets to diacylglycerols. By mediating lipolysis in adipose and non-adipose tissues, ATGL is a major regulator of
