893086-73-2Relevant academic research and scientific papers
An efficient silane-promoted nickel-catalyzed amination of aryl and heteroaryl chlorides
Manolikakes, Georg,Gavryushin, Andrei,Knochel, Paul
, p. 1429 - 1434 (2008)
(Chemical Equation Presented) A new silane-promoted nickel-catalyzed amination of aryl chlorides with 0.5 mol % of Ni(acac)2, 1 mol % of 3,5,6,8-tetrabromo-1,10-phenanthroline, and polymethylhydrosiloxane was developed. A broad range of aryl and heteroaryl chlorides can be coupled with secondary amines and anilines to give the desired (het)arylamines in good to excellent yields. The reaction is sensitive to the nature and amount of the silane promoter.
Anodic cyanation of 1-arylpyrrolidines
Liu, Wei,Ma, Yuan,Yin, Yingwu,Zhao, Yufen
, p. 577 - 579 (2007/10/03)
The electrochemical cyanation of 1-arylpyrrolidines was carried out in methanol containing sodium cyanide at a platinum anode in a divided cell. The reaction gave the corresponding α-aminonitriles 2, together with the unexpected 1-arylpyrrolidine-2-carboximidic acid methyl esters 3 as byproducts.
