89324-44-7

Usage

Uses

Used in Pharmaceutical Research and Organic Synthesis:
5-Formyl-3-thiophenecarboxylic acid serves as a crucial building block in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity contribute to the development of new drugs and organic compounds.
Used in Anti-inflammatory and Anti-cancer Research:
5-Formyl-3-thiophenecarboxylic acid is utilized in research for its potential anti-inflammatory and anti-cancer properties. Its biological activities are of interest for the development of therapeutic agents targeting inflammation and cancer.
Used as an Intermediate in Chemical Production:
In the chemical industry, 5-Formyl-3-thiophenecarboxylic acid is employed as an intermediate in the production of other organic compounds. Its role in the synthesis of a wide range of chemicals underscores its value in chemical research and manufacturing processes.

Upstream product

• 58267-85-9 2-(4-bromo-thiophen-2-yl)-[1,3]dioxolane 
• 88-13-1 3-Thiophene carboxylic acid 
• 100523-84-0 2-bromothiophene-4-carboxylic acid 
• 109-72-8 n-butyllithium 
• 124-38-9 carbon dioxide 

Downstream Products

• 748772-94-3 [2-(2-amino-phenylamino)-ethyl]-[4-(piperidine-1-carbonyl)-thiophen-2-yl-methyl]-carbamic acid tert-butyl ester 
• 748772-98-7 [2-(2-isopropylamino-phenylamino)-ethyl]-[4-(piperidine-1-carbonyl)-thiophen-2-yl-methyl]-carbamic acid tert-butyl ester 
• 67808-66-6 3-methoxycarbonyl-thiophene-5-carboxaldehyde 
• 1196060-27-1 5-(((5S,9R)-9-(4-([14C]-cyano)phenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)methyl)-thiophene-3-carboxylic acid 
• 67808-67-7 5-formyl-3-thiophenecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS

The present invention relates to novel fused heterocyclic ring system compounds and methods for their use in the treatment and prevention of diseases or conditions which are related to irregular calcification.

Substituted heteroarylalkanoic acids

Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C(O)R′, where D, A, and R′ are defined herein. These compounds are useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.

Disubstituted aryl and heteroaryl imines having retinoid-like biological activity

Compounds of the formula STR1 wherein the R 1 groups independently are hydrogen, lower alkyl, or two geminal R 1 groups jointly represent an oxo ( O) or a thio ( S) group; R 2 is hydrogen or lower alkyl, or halogen; M is or --N CR 4 -- or --R 4 C N-- where R 4 is hydrogen or lower alkyl; X is C(R 1) 2 ; Y is phenyl optionally substituted with an R 3 group which is lower alkyl or halogen; A is (CH 2) n where n is 0-5, lower branched chain alkyl, cycloalkyl, alkenyl, alkynyl; B is hydrogen, COOH or a pharmaceutically acceptable salt thereof, COOR 8, CONR 9 R 10, --CH 2 OH, CH 2OR 11, CH 2 OCOR 11, CHO, CH(OR 12) 2, CHOR 13 O, --COR 7, CR 7 (OR 12) 2, or CR 7 OR 13 O, where R 7 is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons, R 8 is an alkyl group of 1 to 10 carbons, or a cycloalkyl group of 5 to 10 carbons, or R 8 is phenyl or lower alkylphenyl, R 9 and R 10 independently are hydrogen, an alkyl group of 1 to 10 carbons, or a cycloalkyl group of 5-10 carbons, or phenyl or lower alkylphenyl, R 11 is lower alkyl, phenyl or lower alkylphenyl, R 12 is lower alkyl, and R 13 is divalent alkyl radical of 2-5 carbons have retinoid-like biological activity.