89339-17-3 Usage
Uses
Used in Pharmaceutical Industry:
3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester is utilized as an intermediate in the synthesis of various pharmaceutical compounds for medicinal purposes. Its unique structure and functional groups contribute to the development of new drugs with potential therapeutic applications.
Used in Drug Synthesis:
In the field of drug synthesis, 3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester serves as a key component in the creation of novel pharmaceutical agents. Its presence in the molecular structure can influence the pharmacokinetics, pharmacodynamics, and overall efficacy of the resulting drug molecules.
Used in Medicinal Research:
3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester is employed as a research tool in medicinal chemistry to explore its potential interactions with biological targets. Understanding these interactions can lead to the discovery of new therapeutic agents and a deeper comprehension of molecular mechanisms in disease processes.
Used in Drug Development:
In the drug development process, 3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester is leveraged to create prototypes and test compounds for preclinical and clinical studies. Its unique properties can aid in optimizing drug candidates for safety, efficacy, and pharmacological profile.
Check Digit Verification of cas no
The CAS Registry Mumber 89339-17-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,3,3 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 89339-17:
(7*8)+(6*9)+(5*3)+(4*3)+(3*9)+(2*1)+(1*7)=173
173 % 10 = 3
So 89339-17-3 is a valid CAS Registry Number.
89339-17-3Relevant academic research and scientific papers
Synthesis and dopamine transporter binding of 2'-substituted cocaine analogs
El-Moselhy, Tarek F.,Avor, Kwasi S.,Basmadjian, Garo P.
, p. 50 - 57 (2007/10/03)
A series of 2'-substituted cocaine analogs (4-8) was synthesized and evaluated in an in vitro dopamine transporter (DAT) system. Compounds 4-7 were prepared by esterifying the 3β-hydroxyl group of ecgonine methyl ester (3) using the appropriate acid chloride in the presence of NEt3 and benzene. Compound 3 was obtained from cocaine (1) by hydrolysis using lN HCl to afford ecgonine HCl which was subjected to acid catalyzed esterification using MeOH saturated with HCl gas. Compound 8 was obtained from 5 by selective trans- esterification with MeOH and HCl gas. The binding affinities of these compounds were determined at DAT for the displacement of [3H]WIN-35428 (2). The 2'-substituted acetoxy and hydroxy analogs exhibited high binding potency for the DAT compared to cocaine (3.5- and 10-fold respectively).
