893412-73-2

Basic information

• Product Name: Hydroxypinacolone Retinoate
• Synonyms: Hydroxypinacolone Retinoate;(2E,4E,6E,8E)-3,3-DIMETHYL-2-OXOBUTYL 3,7-DIMETHYL-9-(2,6,6-TRIMETHYLCYCLOHEX-1-EN-1-YL)NONA-2,4,6,8-TETRAENOATE
• CAS NO: 893412-73-2
• Molecular Formula: C26H38O3
• Molecular Weight: 398.57812
• Mol File: 893412-73-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 508.5±33.0 °C(Predicted)
• Appearance: /
• Density: 0.990±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Hydroxypinacolone Retinoate(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxypinacolone Retinoate(893412-73-2)
• EPA Substance Registry System: Hydroxypinacolone Retinoate(893412-73-2)

Safety Data

• Hazardous Substances Data: 893412-73-2(Hazardous Substances Data)

Usage

Uses

Retinoic Acid 3,3-Dimethyl-2-oxobutyl Ester, is a Retinoic Acid derivative that has shown to be used for treatment of dermatological disorders.

Upstream product

• 38895-88-4 1-hydroxy-3,3-dimethylbutan-2-one 
• 302-79-4 all-trans-retinoic-acid 

Relevant articles and documents

Preparation method of hydroxyl pinacolone retinoate

The invention provides a preparation method of hydroxyl pinacolone retinoate. The preparation method comprises the following steps: preparing corresponding pinacolone by using chloropinacolone through hydrolysis reaction under a strong alkaline condition, and then carrying out condensation reaction on the pinacolone and tretinoin under the conditions of a condensing agent and a catalyst to obtain the hydroxyl pinacolone retinoate. The method is easy to operate, high in reaction yield and suitable for industrial application, and the product obtained through the reaction is free of chloro-pinacolone impurities and can meet the requirement of cosmetics for the quality of the chloro-pinacolone. The invention further provides a novel crystal form of the hydroxyl pinacolone retinoate, and the crystal form is good in stability.