893418-99-0Relevant academic research and scientific papers
Oxidative cleavage of ribofuranose 5-(α-hydroxyphosphonates): a route to erythrofuranose-based nucleoside phosphonic acids
Králíková, ?árka,Budě?ínsky, Milo?,Tome?ková, Ivana,Rosenberg, Ivan
, p. 9742 - 9750 (2007/10/03)
We report here an oxidative cleavage of (5R)- and (5S)-ribofuranosyl-5-C-phosphonate derivatives with periodate anion under both strong acidic and neutral conditions. In both cases, only (5R)-configured compound underwent the expected oxidation reaction a
Nucleoside 5′-C-phosphonates: reactivity of the α-hydroxyphosphonate moiety
Králíková, ?árka,Budě?ínky, Milo?,Masojídková, Milena,Rosenberg, Ivan
, p. 4917 - 4932 (2007/10/03)
We found that various dialkyl phosphites, dialkyl trimethylsilyl phosphites, and tris-trimethylsilyl phosphite reacted smoothly with nucleoside 5′-aldehydes to afford epimeric nucleoside 5′-C-phosphonates in high yields. A number of these compounds in bot
