89371-46-0

Basic information

• Product Name: 4-Imidazolidinecarboxylic acid, 2-oxo-1-(phenylmethyl)-, phenylmethyl ester, (S)-
• CAS NO: 89371-46-0
• Molecular Formula: C18H18N2O3
• Molecular Weight: 310.353
• Mol File: 89371-46-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Imidazolidinecarboxylic acid, 2-oxo-1-(phenylmethyl)-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Imidazolidinecarboxylic acid, 2-oxo-1-(phenylmethyl)-, phenylmethyl ester, (S)-(89371-46-0)
• EPA Substance Registry System: 4-Imidazolidinecarboxylic acid, 2-oxo-1-(phenylmethyl)-, phenylmethyl ester, (S)-(89371-46-0)

Safety Data

• Hazardous Substances Data: 89371-46-0(Hazardous Substances Data)

Upstream product

• 89371-88-0 benzyl (4S)-1-benzyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate 
• 100-39-0 benzyl bromide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 89371-48-2 (4S)-1-benzyl-3-<(2S)-2-amino>propionyl>-2-oxoimidazolidine-4-carboxylic acid 
• 89371-49-3 (S)-1-Benzyl-3-[(S)-2-((S)-1-ethoxycarbonyl-nonylamino)-propionyl]-2-oxo-imidazolidine-4-carboxylic acid 
• 89371-52-8 (4S)-1-benzyl-3-<(2S)-2-amino>propionyl>-2-oxoimidazolidine-4-carboxylic acid 
• 393547-13-2 4-(2-acetylamino-4-tert-butoxycarbonyl-butyrylamino)-4-[1-(1-{5-[1-(allyloxycarbonylmethyl-aminooxalyl)-butylcarbamoyl]-3-benzyl-2-oxo-imidazolidine-1-carbonyl}-2-methyl-propylcarbamoyl)-2-methyl-propylcarbamoyl]-butyric acid tert-butyl ester 
• 393547-03-0 (S)-4-((S)-2-Acetylamino-4-tert-butoxycarbonyl-butyrylamino)-4-((S)-1-{(S)-1-[(S)-5-(1-allylaminooxalyl-butylcarbamoyl)-3-benzyl-2-oxo-imidazolidine-1-carbonyl]-2-methyl-propylcarbamoyl}-2-methyl-propylcarbamoyl)-butyric acid tert-butyl ester 
• 393546-99-1 ((S)-1-{(S)-1-[(S)-5-(1-Allylaminooxalyl-butylcarbamoyl)-3-benzyl-2-oxo-imidazolidine-1-carbonyl]-2-methyl-propylcarbamoyl}-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 811803-63-1 [(S)-1-((S)-1-{(S)-5-[1-(Allylcarbamoyl-hydroxy-methyl)-butylcarbamoyl]-3-benzyl-2-oxo-imidazolidine-1-carbonyl}-2-methyl-propylcarbamoyl)-2-methyl-propyl]-carbamic acid tert-butyl ester 
• 393548-68-0 (3-{[(S)-1-Benzyl-3-((S)-2-tert-butoxycarbonylamino-3-methyl-butyryl)-2-oxo-imidazolidine-4-carbonyl]-amino}-2-hydroxy-hexanoylamino)-acetic acid allyl ester 
• 393547-07-4 (3-{[(S)-1-Benzyl-3-((S)-2-tert-butoxycarbonylamino-3-methyl-butyryl)-2-oxo-imidazolidine-4-carbonyl]-amino}-2-oxo-hexanoylamino)-acetic acid allyl ester 
• 393547-01-8 (S)-3-[(S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-methyl-butyryl]-1-benzyl-2-oxo-imidazolidine-4-carboxylic acid (1-allylaminooxalyl-butyl)-amide 
• 811803-64-2 ((S)-1-{(S)-5-[1-(Allylcarbamoyl-hydroxy-methyl)-butylcarbamoyl]-3-benzyl-2-oxo-imidazolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid tert-butyl ester 
• 393547-09-6 (3-{[(S)-3-((S)-2-Amino-3-methyl-butyryl)-1-benzyl-2-oxo-imidazolidine-4-carbonyl]-amino}-2-oxo-hexanoylamino)-acetic acid allyl ester 
• 393548-62-4 (S)-1-Benzyl-3-((S)-2-tert-butoxycarbonylamino-3-methyl-butyryl)-2-oxo-imidazolidine-4-carboxylic acid benzyl ester 
• 89384-28-1 benzyl (4S)-1-benzyl-3-{(2S)-2-[N-((1S)-1-benzyloxycarbonyl-n-nonyl)amino]propionyl}-2-oxo-imidazolidine-4-carboxylate 

Relevant articles and documents

Novel 2-oxoimidazolidine-4-carboxylic acid derivatives as Hepatitis C virus NS3-4A serine protease inhibitors: Synthesis, activity, and X-ray crystal structure of an enzyme inhibitor complex

Synthesis and HCV NS3 serine protease inhibitory activity of some novel 2-oxoimidazolidine-4-carboxylic acid derivatives are reported. X-ray structure of an inhibitor, 15c bound to the protease is presented. Synthesis and HCV NS3 serine protease inhibitor

ANTIHYPERTENSIVE 2-OXO-IMIDAZOLIDINE DERIVATIVES

Novel 2-oxo-imidazolidine derivative of the formula: STR1 wherein R 1 is lower alkyl or phenyl-lower alkyl, R 2 is lower alkyl, R. sup.3 is alkyl of one to 12 carbon atoms or phenyl-lower alkyl and R 4 is hydrogen or lower alkyl, and a pharmaceutically acceptable salts thereof are disclsoed. Said compounds (I) and salts thereof are useful as hypotensive agents.