893740-97-1

Upstream product

• 106-41-2 4-bromo-phenol 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 112930-90-2 5-bromothiophene-2-carboxaldehyde dimethyl acetal 
• 540-38-5 p-Iodophenol 

Downstream Products

• 940953-30-0 4-[5-({(1R,2R)-2-[(7-Thiophen-2-yl-2,3-dihydro-thieno[3,4-b][1,4]dioxin-5-ylmethyl)-amino]-cyclohexylamino}-methyl)-thiophen-2-yl]-phenol 
• 943241-70-1 4-[5-({(1R,2R)-2-[([2,2']Bithiophenyl-5-ylmethyl)-amino]-cyclohexylamino}-methyl)-thiophen-2-yl]-phenol 
• 1313397-40-8 5-((5-(4-hydroxyphenyl)thiophen-2-yl)methylene)-2-thioxoimidazolidin-4-one 

Relevant academic research and scientific papers

A modular design for minor groove binding and recognition of mixed base pair sequences of DNA

The design and synthesis of compounds that target mixed, AT/GC, DNA sequences is described. The design concept connects two N-methyl-benzimidazole-thiophene single GC recognition units with a flexible linker that lets the compound fit the shape and twist of the DNA minor groove while covering a full turn of the double helix.

Epoxy platinum complex as well as preparation method and application thereof

The invention relates to an epoxy platinum complex as well as a preparation method and application thereof, the epoxy platinum complex has a structure as shown in a formula I, the epoxy platinum complex can recognize tyrosinase through fluorescence change, experimental verification proves that the epoxy platinum complex has melanoma and breast cancer cell resisting activity, and the series of compounds can be used as antitumor drugs and can be used for preparing anti-tumor drugs. And a foundation is laid for photodynamic tumor treatment.

Novel 2-(5-aryl)thiophen-2-yl)benzimidazoles; design, synthesis and in vitro evaluation against cercarial phase of schistosoma mansoni

Background: Literature survey has pointed out that Benzimidazoles represent an interesting class of anthelmintics, of which several potent members were developed. Objective: Benzimidazoles hybridized with pharmacophoric moieties possessing anthelmintic ac

Geometry relaxation-induced large stokes shift in red-emitting borondipyrromethenes (BODIPY) and applications in fluorescent thiol probes

2-Thienyl and 2,6-bisthienyl BODIPY derivatives (BS-SS and BS-DS) were prepared that show intense absorption (ε = 65000 M-1 cm -1 at 507 nm) and a large Stokes shift (96 nm) vs the small Stokes shift of typical BODIPY (15 nm). Contr

COMPOUNDS, PREPARATIONS AND USES THEREOF

The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as agents or drugs for inhibiting perforin activity and for treating a subject at risk of or susc

2-Arylthienyl-substituted 1,3-benzothiazoles as new nonlinear optical chromophores

A series of nonlinear optical chromophores 6 containing a substituted benzothiazole ring have been synthesized and characterized. 1,3-Benzothiazoles 6 were prepared by treating various formyl derivatives of thienyl compounds with ortho-aminobenzenethiol i