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89376-77-2

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89376-77-2 Usage

General Description

"(10xi)-17-ethynyl-10-hydroperoxy-17-hydroxyestra-1,4-dien-3-one" is a synthetic hormone compound with potent hormonal activity. It is a derivative of estradiol, a hormone that plays a key role in regulating the female reproductive system. The compound contains a hydroperoxy group, which is a rare structural feature in natural steroid hormones. This unique structure gives the compound its distinctive properties, which may make it useful for potential therapeutic applications. Further research is needed to fully understand its biological effects and potential uses.

Check Digit Verification of cas no

The CAS Registry Mumber 89376-77-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,3,7 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 89376-77:
(7*8)+(6*9)+(5*3)+(4*7)+(3*6)+(2*7)+(1*7)=192
192 % 10 = 2
So 89376-77-2 is a valid CAS Registry Number.

89376-77-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 17α-Ethynyl-10β-hydroperoxy-1,4-estradiene-17β-ol-3-one

1.2 Other means of identification

Product number -
Other names (8S,9S,10S,13S,14S,17R)-17-Ethynyl-10-hydroperoxy-17-hydroxy-13-methyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89376-77-2 SDS

89376-77-2Upstream product

89376-77-2Downstream Products

89376-77-2Relevant articles and documents

Photosensitized decomposition of contraceptive steroids: A possible explanation for the observed (photo)allergy of the oral contraceptive pill

Sedee,Beijersbergen van Henegouwen

, p. 111 - 119 (1985)

The photo-sensitized decomposition of the main steroids used in the oral contraceptive pill has been studied. Under the circumstances applied, 1 and 8 decomposed rapidly (t( 1/2 ) = 11.0 ± 0.2 min for 1 and 5.7 ± 0.4 min for 8). The decomposition product of 1 has been identified as 17α-ethynyl-10β-hydroperoxy-17β-hydroxyestra-1,4-dien-3-one (2). The decomposition products of 1 and 8 were previously found in experiments in which the irreversible binding of these steroids to protein was studied. Photosensitized decomposition of the steroids may be the cause of (photo)allergic side-effects of 'the pill'. The photosensitized decomposition of the main steroids used in oral contraceptives was studied. Under the circumstances applied, ethinyl estradiol and norethynodrel decomposed rapidly (t 1/2 = 11.0 + or - 0.2 minutes for ethinyl estradiol and 5.7 + or - 0.4 minutes for norethynodrel). The decomposition product of ethinyl estradiol has been identified as 17 alpha-ethynyl-10 beta-hydroperoxy-17 beta-hydroxyestra-1,4-dien-3-one. The decomposition products of ethinyl estradiol and norethnodrel were previously found in experiments in which the irreversible binding of these steroids to protein was studied. Photosensitized decomposition of the steroids may be the cause of photoallergic side effects of "the pill." author's modified

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