893772-96-8

Upstream product

• 1063625-01-3 (Z)-3-[(1,2,3-trimethyl-1H-indol-4-yl)amino]-1,3-diphenyl-2-propen-1-one 
• 143797-94-8 1,2,3-trimethyl-1H-indol-5-ylamine 
• 100-52-7 benzaldehyde 
• 536-74-3 phenylacetylene 

Relevant academic research and scientific papers

One-pot synthesis of pyrrolo[3,2-f]-and pyrrolo[2,3-h]quinoline derivatives: Observation of an unexpected mechanistic pathway

One-pot synthesis of pyrrolo[3,2-f]- and pyrrolo[2,3-h]quinolines were obtained starting from substituted 5-aminoindoles, benzaldehydes, and phenylacetylenes in the presence of La(OTf)3 as a catalyst in good yields. The indole moiety in 5-aminoindole is believed to be mainly responsible for the observation of unexpected mechanistic pathway to the formation of pyrrolo[2,3-h]quinoline. Georg Thieme Verlag Stuttgart · New York.

Synthesis of pyrrolo[2,3-H]quinolines from 4-amino-2,3-dimethyl-and 4-amino-1,2,3-trimethylindoles

A study was carried out on the reactions of 4-amino-2,3-dimethyl-and 4-amino-1,2,3-trimethylindoles with acetylacetone, dibenzoylmethane, ethyl acetoacetate, ethyl trifluoroacetoacetate, and ethyl oxaloacetate. Methods were developed for the synthesis of a series of substituted pyrrolo-[2,3-h] quinolines.