89415-43-0

Basic information

• Product Name: 4-Aminophenylboronic acid
• Synonyms: 4-AMINOPHENYLBORONIC ACID;4-AMINOBENZENEBORONIC ACID;4-Aminobenzeneboronic acid 96%;4-AMINOPHENYLBORONICACIDHCI;(4-Anilino)boronic acid;B-(4-Aminophenyl)-boronic acid;Benzeneboronic acid, p-amino- (6CI,7CI);Boronic acid, (4-aminophenyl)- (9CI)
• CAS NO: 89415-43-0
• Molecular Formula: C₆H₈BNO₂
• Molecular Weight: 136.94
• Product Categories: Boron compounds;blocks;BoronicAcids;Boric Acid;Substituted Boronic Acids;Boronic Acid;Boronate Ester;Potassium Trifluoroborate
• Mol File: 89415-43-0.mol
• Article Data: 10

Chemical Properties

• Melting Point: 62-66
• Boiling Point: 355 °C at 760 mmHg
• Flash Point: 168.5 °C
• Appearance: /
• Density: 1.23
• Storage Temp.: Store Cold
• PKA: 8.82±0.10(Predicted)
• CAS DataBase Reference: 4-Aminophenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Aminophenylboronic acid(89415-43-0)
• EPA Substance Registry System: 4-Aminophenylboronic acid(89415-43-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36/37/39-36
• Hazardous Substances Data: 89415-43-0(Hazardous Substances Data)

Usage

Chemical Properties

Crystalline powder

Uses

4-Aminophenylboronic Acid is a compound being used in the discovery of multi-target receptor tyrosine kinase inhibitors as novel anti-angiogenesis agents.

Upstream product

• 24067-17-2 4-nitrophenylboronic acid 
• 64-17-5 ethanol 
• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 
• 121-43-7 Trimethyl borate 
• 7732-18-5 water 
• 106-40-1 4-bromo-aniline 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 82261-42-5 4-pyridin-3-ylaniline 
• 397843-87-7 N-(phenylaminocarbonyl)-4-aminophenylboronic acid 
• 397843-80-0 N-(benzoyl)-4-aminophenylboronic acid 
• 1141-39-5 1-(4'-amino-biphenyl-4-yl)-ethanone 
• 1027706-07-5 {4-[(1,3-thiazol-4-ylcarbonyl)amino]phenyl}boronic acid 

Relevant articles and documents

COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

A compound according to an embodiment of the present disclosure is represented by Formula 1: When the compound is used in an organic light-emitting device, efficiency is higher as compared to when existing compounds in the art are used. In particular, the compound shows a remarkable effect of lifespan improvement, resulting in a significantly increased lifespan of the organic light-emitting device including the compound.

Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters

The present invention relates to a process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters of formula (I) in high yields The claimed process uses diarylketal formula (V) to generate an arylbromid of formula (III) in which the amino-group is protected as bisarylmethylidenimino-group:

Susceptibility to hydrolysis of phenylboronic pinacol esters at physiological pH

Boronic acids and their esters are highly considered compounds for the design of new drugs and drug delivery devices, particularly as boron-carriers suitable for neutron capture therapy. However, these compounds are only marginally stable in water. Hydrol