89434-91-3Relevant articles and documents
SYNTHESIS AND STRUCTURE OF SUBSTITUTED 3,4-DIHYDROPYRIDIN-2-ONES
Krauze, A. A.,Liepin'sh, E. E.,Kalme, Z. A.,Pelcher, Yu. E.,Dubur, G. Ya.
, p. 1241 - 1245 (2007/10/02)
The condensation of benzylideneacetoacetic ester with cyanoacetamide in the presence of triethylamine yielded 3-carbamoyl-3,4-dihydropyridin-2-one, while the condensation of arylidenecyanoacetamides with β-aminocrotonic ester in acetic acid yielded 3-cyano-3,4-dihydropyridin-2-ones.It was established by NMR spectroscopy that 3-cyano-4-R-5-ethoxycarbonyl-6-methyl-3,4-dihydropyridin-2-ones exist in solutions in the form of a mixture of cis- and trans-stereosiomers in a 10:1 ratio.