894810-84-5

Upstream product

• 1242061-77-3 N-(6-chloro-2-formylphenyl)-4-methylbenzenesulfonamide 
• 106-95-6 allyl bromide 
• 247237-41-8 N-p-toluenesulfonyl-3-chloroanthranilic acid methyl ester 
• 77820-58-7 methyl 3-chloroanthranilate 
• 6388-47-2 2-amino-3-chlorobenzoic acid 
• 894810-82-3 N-allyl-N-p-toluenesulfonyl-3-chloroanthranilic acid methyl ester 
• 894810-83-4 N-allyl-N-p-toluenesulfonyl-2-chloro-6-(hydroxymethyl)aniline 

Downstream Products

• 143262-07-1 7-chloro-N-p-tolylsulfonylindole 
• 894810-43-6 N-allyl-N-(2-chloro-6-vinyl-phenyl)-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

Pd-Catalyzed Migratory Cycloisomerization of N-Allyl- o-allenylaniline Derivatives

The Pd-catalyzed migratory cycloisomerization of N-allyl-o-allenyl aniline derivatives is first reported to give indoles having a substituent at the 2-position.

Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles

A pure ruthenium hydride complex with N-heterocyclic carbene (NHC) ligand was efficiently generated from the reaction of a second-generation Grubbs ruthenium catalyst with vinyloxytrimethylsilane and unambiguously characterized. This ruthenium hydride complex showed high catalytic activity for the selective isomerization of terminal olefin and for the cycloisomerization of 1,6-dienes. These reactions of N-allyl-o-vinylaniline lead to novel synthetic methods for heterocycles such as indoles and 3-methylene-2,3-dihydroindoles, which are useful synthons for bioactive natural products. These procedures address an important issue in diversity-oriented synthesis.