89483-06-7

Basic information

• Product Name: BOC-L-CYCLOPROPYLALANINE-DCHA
• Synonyms: BOC-ALA(BETA-CYCLOPROPYL)-OH DICYCLOHEXYLAMMONIUM SALT;BOC-ALA(CPRO)-OH DCHA;BOC-ALA(CYCLOPROPYL)-OH DCHA;BOC-BETA-CYCLOPROPYL-L-ALANINE DCHA;BOC-BETA-CYCLOPROPYL-L-ALA-OH DCHA;BOC-BETA-CYCLOPROPYL-ALANINE DCHA;BOC-BETA-CYCLOPROPYL-ALA-OH DCHA;N-ALPHA-T-BUTOXYCARBONYL-3-CYCLOPROPYL-L-ALANINE DICYCLOHEXYLAMMONIUM SALT
• CAS NO: 89483-06-7
• Molecular Formula: C₁₁H₁₉NO₄
• Molecular Weight: 410.59
• Mol File: 89483-06-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 377.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.162±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 4.00±0.10(Predicted)
• CAS DataBase Reference: BOC-L-CYCLOPROPYLALANINE-DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-L-CYCLOPROPYLALANINE-DCHA(89483-06-7)
• EPA Substance Registry System: BOC-L-CYCLOPROPYLALANINE-DCHA(89483-06-7)

Safety Data

• Hazardous Substances Data: 89483-06-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 102735-53-5 (2S)-2-amino-3-cyclopropylpropanoic acid 
• 104347-84-4 methyl (S)-2-((tert-butoxycarbonyl)amino)-3-cyclopropylpropanoate 

Downstream Products

• 905927-61-9 {2-[3-(2-tert-butoxycarbonylamino-3-cyclopropyl-propionylamino)-4-cyclopropyl-2-hydroxy-butyrylamino]-acetylamino}-phenyl-acetic acid tert-butyl ester 

Relevant articles and documents

Inhibitors of cysteine proteases and methods of use thereof

The disclosure provides compounds with warheads and their use in treating medical diseases or disorders, such as viral infections. Pharmaceutical compositions and methods of making various compounds with warheads are provided. The compounds are contemplated to inhibit proteases, such as the 3C, CL- or 3CL-like protease. Exemplary compounds provided include Formula II-I, where R3, RB are provided herein:

ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS

The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.

Protease inhibitors

The present invention provides compounds of formula (I) which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia or malignancy; and metabolic bone disease therewith.