Isonicotinic acid-[1-(4-hydroxy-phenyl)-propylidenehydrazide], also known as isoniazid, is a potent first-line antituberculosis drug. It is a hydrazide derivative of isonicotinic acid, with the chemical structure featuring a 4-hydroxyphenyl group attached to a propylidene bridge. Isoniazid works by inhibiting bacterial cell wall synthesis in Mycobacterium tuberculosis, the causative agent of tuberculosis. It is particularly effective during the active replication phase of the bacteria. The drug is metabolized in the liver and can cause side effects such as hepatotoxicity and peripheral neuropathy, which can be mitigated by the concurrent administration of pyridoxine. Isoniazid is a key component in the standard treatment regimens for tuberculosis and is often combined with other antibiotics to prevent drug resistance.
895-66-9
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Basic information
- Product Name: isonicotinic acid-[1-(4-hydroxy-phenyl)-propylidenehydrazide]
- Synonyms:
- CAS NO:895-66-9
- Molecular Formula:
- Molecular Weight: 269.303
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: isonicotinic acid-[1-(4-hydroxy-phenyl)-propylidenehydrazide](CAS DataBase Reference)
- NIST Chemistry Reference: isonicotinic acid-[1-(4-hydroxy-phenyl)-propylidenehydrazide](895-66-9)
- EPA Substance Registry System: isonicotinic acid-[1-(4-hydroxy-phenyl)-propylidenehydrazide](895-66-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 895-66-9(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 895-66-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,9 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.Calculate Digit Verification of CAS Registry Number 895-66:
(5*8)+(4*9)+(3*5)+(2*6)+(1*6)=109
109 % 10 = 9
So 895-66-9 is a valid CAS Registry Number.
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isonicotinic acid-[1-(4-hydroxy-phenyl)-propylidenehydrazide]
