89510-72-5Relevant academic research and scientific papers
Synthesis of biphenyltrienes as probes for β-amyloid plaques
Zhuang, Zhi-Ping,Kung, Mei-Ping,Kung, Hank F.
, p. 2841 - 2844 (2007/10/03)
We report a series of p-hydroxy-, p-amino-, p-monomethylamino-, and p-monofluoroethylamino-substituted biphenyltrienes that displayed high binding affinities to β-amyloid plaques. In an in vitro binding assay using postmortem brain homogenates of Alzheime
Effective and highly stereoselective coupling with vinyldiazomethanes to form symmetrical trienes
Doyle, Michael P.,Yan, Ming
, p. 602 - 604 (2007/10/03)
Diazo coupling reactions are capable of forming E,E,E-trienes from cinnamaldehydes in good yield. An efficient methodology is reported for the production of styryldiazomethanes that are subsequently used with catalysis for coupling and for cyclopropanatio
Preparation of p,p'-Disubstituted-α,ω-Diphenyl Polyenes
Spangler, Charles W.,McCoy, Ray K.,Dembek, Alexa A.,Sapochak, Linda S.,Gates, Bradley D.
, p. 151 - 154 (2007/10/02)
Condensation of appropriately substituted benzaldehydes or cinnamaldehydes with either bis-Wittig reagents or bis-phosphonate esters (Horner-Emmons-Wadsworth modifications) containing one or two double bond units are general and quite efficient preparatio
