895159-96-3Relevant academic research and scientific papers
Highly enantioselective catalytic asymmetric synthesis of a (R)-sibutramin precursor
Berens, Ulrich,Hafner, Andreas,Dosenbach, Oliver,Tritschler, Tanja,Schwarzenbach, Franz,Kirner, Hans-Jorg,Malan, Christophe,Mai-Huynh, Oanh
, p. 59 - 64 (2010)
The first highly enantioselective, catalytic asymmetric synthesis of di-des-methylsibutramine 3 is described. Dienamide 10, prepared by acetic acid anhydride quenching of the condensation product of nitrile 4 with a methallyl magnesium chloride, proved to
ENANTIOSELECTIVE SYNTHESIS OF A STERICALLY HINDERED AMINE
-
Page/Page column 17, (2008/06/13)
Compounds of the formula (I) wherein R is phenyl, or phenyl substituted by Cl, Br, C1-C4alkyl or CF3; R1 is H or methyl or ethyl; R2 is H or methyl or acyl; R3 is H or methyl; R'4/sub
