89525-50-8

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 75-64-9 tert-butylamine 
• 46190-12-9 C₁₁H₁₆NCl 

Downstream Products

• 46190-12-9 C₁₁H₁₆NCl 
• 1426320-86-6 2-chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 
• 52839-45-9 3,4-diphenylisoquinoline 

Relevant academic research and scientific papers

Highly Regioselective Isoquinoline Synthesis via Nickel-Catalyzed Iminoannulation of Alkynes at Room Temperature

A simple and cost-efficient nickel catalytic system for the annulation of 2-haloaldimines with alkynes to synthesize 3,4-disubstituted and 3-substituted isoquinolines at room temperature has been developed. The air-stable and inexpensive Ni(dppe)Cl2 was employed as a precatalyst, and Et3N was found to be an essential additive for obtaining high yields. By using this nickel catalytic system one-pot three-component direct synthesis of isoquinolines starting with simple 2-halobenzaldehydes, tert-butylamine, and alkynes were also achieved. These reactions occur in moderate to excellent yields with complete regioselectivity. Moreover, these reactions feature a broad substrate scope, easy scalability, operational simplicity, and excellent practicality.

Formal Ir-Catalyzed Ligand-Enabled Ortho and Meta Borylation of Aromatic Aldehydes via in Situ-Generated Imines

The ligand-enabled development of ortho and meta C-H borylation of aromatic aldehydes is reported. It was envisaged that while ortho borylation could be achieved using tert-butylamine as the traceless protecting/directing group, meta borylation proceeds via an electrostatic interaction and a secondary interaction between the ligand of the catalyst and the substrate. These ligand-substrate electrostatic interactions and secondary B-N interactions provide an unprecedented controlling factor for meta-selective C-H activation/borylation.

Well-defined BiOCl colloidal ultrathin nanosheets: Synthesis, characterization, and application in photocatalytic aerobic oxidation of secondary amines

We demonstrate the first colloidal synthesis of single-crystalline BiOCl ultrathin nanosheets (UTNSs) that feature a well-defined square morphology. Unlike BiOCl nanomaterials prepared by hydrothermal routes, our colloidal BiOCl UTNSs exhibit hydrophobic

Photocatalytic aerobic oxidation of amines to imines on BiVO4 under visible light irradiation

BiVO4 was found to be an efficient photocatalyst under visible light irradiation for selective oxidation of amines to imines with high activity (99% conversion) and selectivity (up to 99%) using oxygen as an oxidant.

Kinetic control of the direction of inclusion of nitroxide radicals into cyclodextrins

N-benzyl-tert-butyl nitroxide derivatives substituted at the aromatic ring form host-guest inclusion complexes with β-and γ-cyclodextrin. They were employed as probes to assess substituent effects on the geometry of the complex and on the kinetics of this

Methyl-phenyl derivatives, preparation method and use

The present invention relates to: a) methylbiphenyl derivatives of general formula: in which R1represents OH, C3-C7alkyl or C3-C7cycloalkyl, these compounds being in the form of individual isomers or mixtures thereof, b) their preparation by reaction: either of a hydroxylamine salt with an N-substituted o-(p-tolyl)benzaldimine, to give o-(p-tolyl)benzaldoxime or of an N-substituted 2-halobenzaldimine with a p-tolylmagnesium halide in the presence of an inorganic manganese derivative, to give the compounds of formula I in which R1represents C3-C7alkyl or C3-C7cycloalkyl c) their use for the preparation of o-(p-tolyl)-benzonitrile, which is an intermediate in the synthesis of medicinal products.