89546-87-2

Basic information

• Product Name: 3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridine
• Synonyms: 3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridine;2-Methyl-5-(pyridin-3-yl)-1,3,4-oxadiazole
• CAS NO: 89546-87-2
• Molecular Formula: C8H7N3O
• Molecular Weight: 161.16068
• Mol File: 89546-87-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridine(89546-87-2)
• EPA Substance Registry System: 3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridine(89546-87-2)

Safety Data

• Hazardous Substances Data: 89546-87-2(Hazardous Substances Data)

Usage

General Description

3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridine is a chemical compound with the molecular formula C8H7N3O, consisting of carbon, hydrogen, nitrogen, and oxygen atoms. It is a pyridine derivative with a substituted oxadiazole ring, making it a heterocyclic compound. This chemical has potential applications in pharmacology and drug development due to its ability to interact with biological systems. Its unique structure and properties make it a valuable building block for the synthesis of new pharmaceutical compounds, and it may also have other industrial uses due to its reactivity and functional groups. Further research and development of this compound could lead to its use in various fields such as medicine, agriculture, and materials science.

Upstream product

• 553-53-7 Nicotinic acid hydrazide 
• 127-19-5 N,N-dimethyl acetamide 
• 79-24-3 Nitroethane 
• 78-39-7 Triethyl orthoacetate 
• 3250-74-6 3-(1H-tetrazol-5-yl)pyridine 
• 108-24-7 acetic anhydride 
• 7254-31-1 N'-acetylpyridine-3-carbohydrazide 
• 3250-74-6 3-(2H-tetrazole-5-yl)pyridine 

Downstream Products

• 1208535-65-2 3-(3-methyl-5-(pyridin-3-yl)-1,2,4-triazol-4-yl)benzoic acid 
• 1208535-64-1 4-(3-methyl-5-(pyridin-3-yl)-1,2,4-triazol-4-yl)benzoic acid 

Relevant articles and documents

TiCl4 mediated facile synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

An efficient method for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles has been developed. Various hydrazides or thionyl hydrazides readily react with DMA derivatives in the presence of TiCl4 as a catalyst to afford the desired products. This protocol provides a simple and economical procedure that affords the target products with good yields and wide substrate scope.

Trifluoromethanesulfonic acid-Ag(I) complex based on 3-(5-methyl-1,3,4-oxadiazole)pyridine and synthetic method thereof

The invention discloses a trifluoromethanesulfonic acid-Ag(I) complex based on 3-(5-methyl-1,3,4-oxadiazole)pyridine and a synthetic method thereof. The trifluoromethanesulfonic acid-Ag(I) complex hasa general chemical formula of {[Ag3(L)4].3CF3SO3}, wherein L is 3-(5-methyl-1,3,4-oxadiazole)pyridine used as a ligand. The synthetic method comprises the following steps: weighing AgCF3SO3 and the ligand namely 3-(5-methyl-1,3,4-oxadiazole)pyridine according to a mol ratio as shown in the general chemical formula of {[Ag3(L)4].3CF3SO3}, carrying out uniform mixing, carrying out a reaction at 150to 180 DEG C, and carrying out natural cooling to a room temperature of 20 to 25 DEG C so as to obtain a white transparent crystal, i.e., the complex provided by the invention. The complex provided by the invention shows adsorption properties to a variety of dyes, and has application potential.

Syntheses, structural diversities and characterization of a series of coordination polymers with two isomeric oxadiazol-pyridine ligands

In this work two positional-isomeric oxadiazol-pyridine ligands 3-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (L1) and 4-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (L2) have been designed and synthesized. A series of novel coordination polymers, namely [Cd2(μ2-L1)2(μ2-NCS)4]n (1), {[Cd(L1)(μ2-dca)2(H2O)]·H2O}n (2), {[Cu(μ2-L1)2(NCS)2]·0.5H2O}n (3), {[Ag2(μ2-L1)(μ3-L1)2]·2PF6}n (4), {[Ag3(μ2-L1)4(μ2-CF3SO3)(CF3SO3)]·CF3SO3} (5), {[Cd(L2)2(μ2-NCS)2]}n (6), [Ag(μ2-L2)(μ2-CF3SO3)]n (7) and {[Ag(μ2-L2)]·BF4}n (8) have been isolated. Both 1 and 2 are 2D CdII coordination polymers containing infinite {Cd-NCS-Cd} chains (for 1) or infinite {Cd-dca-Cd} layers (for 2), respectively. 3 is a 2D CuII coordination polymer, in which central metal ions are bridged via a bidentate bridging L1 ligand. While when different AgI salts were introduced into the reaction system, 1D AgI coordination polymers 4 and 5 with diverse coordination modes can be isolated. Furthermore, when the isomeric oxadiazol-pyridine L2 is used to replace L1 in the reaction system, 6-8 can be isolated. 6 is a 2D CdII coordination polymer containing {Cd-NCS-Cd} layers. 7 is a 2D neutral AgI coordination polymer while 8 is a 2D cationic AgI coordination polymer. Variable temperature magnetic susceptibility measurements (2-300 K) reveal anti-ferromagnetic interactions between central copper(ii) ions for 3. Solid-state luminescent properties of 1, 2 and 4-8 have been investigated indicating strong fluorescent emissions. Additionally, luminescent measurements illustrate that complex 8 exhibits highly sensitive luminescence sensing for Cr2O72? ions in aqueous solutions with high quenching efficiency Ksv = 2.08 × 104 L mol?1 and low detection limit (0.19 μM (S/N = 3)). 8 also represents the first report of a coordination polymer based on oxadiazol-pyridine derivatives with a luminescence response to Cr2O72? anion pollutants in aqueous solutions.