895572-22-2Relevant academic research and scientific papers
Synthetic chemistry-led creation of a difluorinated biaryl ether non-nucleoside reverse transcriptase inhibitor
Jones, Lyn H.,Randall, Amy,Barba, Oscar,Selby, Matthew D.
, p. 3431 - 3433 (2008/09/19)
In the process of developing a series of novel, fluorinated biaryl ether NNRTIs, we fortuitously discovered derivative 20, which possesses excellent potency against both wild-type and clinically relevant mutations of the reverse transcriptase enzyme. The
CHEMICAL COMPOUNDS
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Page/Page column 23, (2008/06/13)
This invention relates to biaryl ether derivatives of formula (I), wherein R1, R3, R4, X, W, Y and m are defined in the description, and to compositions containing them and the uses of such derivatives. The compounds of th
