895579-06-3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 895579-11-0 3-(allyldimethylsilyl)prop-2-yn-1-ol 
• 895579-14-3 (E)-3-(allyldimethylsilyl)acrylaldehyde 
• 895579-17-6 (2R,3R)-ethyl 1-(4-methoxybenzyl)-3-(allyldimethylsilyl)-2-cyano-5-oxopyrrolidine-2-carboxylate 
• 895579-25-6 (2R,3R,4S)-3-(Allyl-dimethyl-silanyl)-2-hydroxymethyl-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carbonitrile 
• 895579-04-1 (2R,3R,4S)-3-(Allyl-dimethyl-silanyl)-2-formyl-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carbonitrile 
• 895579-15-4 ethyl 2-(4-methoxybenzylamino)-2-cyanoacetate 
• 895579-05-2 (2R,3R,4S)-3-(Allyl-dimethyl-silanyl)-2-((S)-1-hydroxy-2-methyl-allyl)-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carbonitrile 
• 895579-24-5 (2R,3R,4S)-3-(Allyl-dimethyl-silanyl)-2-cyano-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid ethyl ester 
• 895579-03-0 (E)-N-(3-(allyldimethylsilyl)acryloyl)benzamide 
• 895579-13-2 (E)-3-(allyldimethylsilyl)acrylic acid 
• 895579-12-1 (E)-3-(allyldimethylsilyl)prop-2-en-1-ol 

Downstream Products

• 133343-34-7 Lactacystin 
• 895579-08-5 Trifluoro-methanesulfonic acid (1S,4R,7R,8R)-1-isopropyl-5-(4-methoxy-benzyl)-7-methyl-3,6-dioxo-2-oxa-5-aza-spiro[3.4]oct-8-yl ester 
• 895579-07-4 (2S,3R,4R)-3-Hydroxy-2-((S)-1-hydroxy-2-methyl-allyl)-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid 
• 895579-27-8 (2R,3R,4R)-3-Hydroxy-2-((S)-1-hydroxy-2-methyl-propyl)-1-(4-methoxy-benzyl)-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid 
• 895579-28-9 (3S,4S,7R,8S)-8-Hydroxy-3-isopropyl-5-(4-methoxy-benzyl)-7-methyl-2-oxa-5-aza-spiro[3.4]octane-1,6-dione 
• 895579-29-0 (3S,4S,7R,8R)-8-Hydroxy-3-isopropyl-5-(4-methoxy-benzyl)-7-methyl-2-oxa-5-aza-spiro[3.4]octane-1,6-dione 
• 895579-26-7 (3S,3aS,6S,6aR)-3-Isopropenyl-4-(4-methoxy-benzyl)-1,1,6-trimethyl-5-oxo-tetrahydro-2-oxa-4-aza-1-sila-pentalene-3a-carboxylic acid 

Relevant academic research and scientific papers

α,β-unsaturated β-silyl lmide substrates for catalytic, enantioselective conjugate additions: A total synthesis of (+)-lactacystin and the discovery of a new proteasome inhibitor

Chiral (salen)Al μ-oxo dimer 1 catalyzes the highly enantioselective conjugate addition of carbon-centered nucleophiles to α,β-unsaturated silyl imides. Allyldimethylsilane-substituted imide 4 was identified as an optimal substrate, undergoing addition re