89575-10-0

Basic information

• Product Name: N-VANILLYLHEPTANAMIDE
• Synonyms: N-VANILLYLHEPTANAMIDE;VANILLYLHEPTOYLAMIDE
• CAS NO: 89575-10-0
• Molecular Formula: C₁₅H₂₃NO₃
• Molecular Weight: 265.348
• Mol File: 89575-10-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 473°Cat760mmHg
• Flash Point: 239.9°C
• Appearance: /
• Density: 1.062g/cm³
• Vapor Pressure: 1.43E-09mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: N-VANILLYLHEPTANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-VANILLYLHEPTANAMIDE(89575-10-0)
• EPA Substance Registry System: N-VANILLYLHEPTANAMIDE(89575-10-0)

Safety Data

• Hazardous Substances Data: 89575-10-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H23NO3/c1-3-4-5-6-7-15(18)16-11-12-8-9-13(17)14(10-12)19-2/h8-10,17H,3-7,11H2,1-2H3,(H,16,18)

Upstream product

• 111-14-8 oenanthic acid 
• 7149-10-2 vanillylamine hydrochloride 
• 1196-92-5 Vanillylamin 
• 2528-61-2 Heptanoic acid chloride 

Relevant articles and documents

Vanilla amide synthesis method

The invention discloses a vanilla amide synthesis method, which comprises the following step: by taking alcohol and vanilla amide as raw materials, or aldehyde and vanilla amide as raw materials, inorganic ferric salt and inorganic indium salt as a composite catalyst and oxygen as an oxidant, carrying out one-pot reaction in an organic solvent to generate vanilla amide. The synthesis raw materials adopted by the synthesis method are wide in source, a large amount of chemical reaction waste can be avoided in the whole reaction process, and the synthesis method is clean and environmentally friendly, has the advantages of mild and controllable reaction conditions, simple operation, convenience in product separation and purification, high product yield, wide universality of reaction substrates and the like, and is a method suitable for industrial production.

Vanilloids. 1. Analogs of Capsaicin with Antinociceptive and Antiinflammatory Activity

As part of a program to establish structure-activity relationships for vanilloids, analogs of the pungent principle capsaicin, the alkyl chain portion the parent structure (and related compounds derived from homovanillic acid) was varied.In antinociceptive and antiinflammatory assays (rat and mouse hot plate and croton oil-inflamed mouse ear), compounds with widely varying alkyl chain structures were active.Short-chain compounds were active by systemic administration in the assays mentioned above but they retained the high pungency and acute toxicity characteristic of capsaicin.In contrast, the long chain cis-unsaturates, NE-19550 (vanillyloleamide) and NE-28345 (oleylhomovanillamide), were orally active, less pungent, and less acutely toxic than capsaicin.The potential of these compounds as antiinflammatory/analgesic agents is discussed in light of recent data on the mechanism of action of vanilloids on sensory nerve fibers.