89576-29-4

Basic information

• Product Name: 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
• Synonyms: 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE;18:1 LYSO PE;1-Oleoyl-2-hydroxy-sn-glycero-3-PE
• CAS NO: 89576-29-4
• Molecular Formula: C23H45NO7P-
• Molecular Weight: 478.58
• Mol File: 89576-29-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 597.4±60.0 °C(Predicted)
• Appearance: /
• Density: 1.086±0.06 g/cm3(Predicted)
• PKA: 1.14±0.50(Predicted)
• CAS DataBase Reference: 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE(89576-29-4)
• EPA Substance Registry System: 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE(89576-29-4)

Safety Data

• Hazardous Substances Data: 89576-29-4(Hazardous Substances Data)

Usage

Uses

1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine is used as a biomarker of multiple myeloma development and progression.

Upstream product

• 3927-73-9 1-oleoyl-2-stearoyl-sn-glycero-3-phosphoethanolamine 
• 34487-30-4 (9Z)-9-octadecenoate-(2’S)-2’,3’-dihydroxypropyl ester 
• 112-80-1 cis-Octadecenoic acid 
• 1609563-03-2 2-O-tert-butyldimethylsilanyl-1-O-cis-octadec-9-enoyl-sn-glycerol 
• 113019-11-7 2-(((4-methoxyphenyl)diphenylmethyl)amino)ethanol 
• 150447-02-2 (S)-2,2-dimethyl-1,3-dioxolan-4-ylmethyl (Z)-9-octadecenoate 

Downstream Products

• 112-80-1 cis-Octadecenoic acid 

Relevant articles and documents

Synthesis and evaluation of immunostimulant plasmalogen lysophosphatidylethanolamine and analogues for natural killer T cells

Plasmalogen lysophosphatidylethanolamine (pLPE) had been identified as a self antigen for natural killer T cells (NKT cells). It is very important in the development, maturation and activation of NKT cells in thymus. Besides, pLPE is a novel type of antigen for NKT cells. To evaluate the structure-activity relationship (SAR) of this new antigen, pLPE and its analogues referred to different aliphatic chains and linkages at the sn-1 position of the glycerol backbone were synthesized, and the biological activities of these analogues was characterized. It is discovered that the linkages between phosphate and lipid moiety are not important for the antigens' activities. The pLPE analogues 1, 3, 4, 7 and 9, which have additional double bonds on lipid parts, were identified as new NKT agonists. Moreover, the analogues 4, 7 and 9 were discovered as potent Th2 activators for NKT cells.