89595-83-5

Upstream product

• 25487-25-6 PheCH₂Cl, HBr 
• 26049-92-3 Z-Ala-PheCH₂Cl 
• 3057-69-0 N-[(benzyloxy)carbonyl]-L-alanyl-L-alanyl-L-alanine methyl ester 
• 2483-51-4 N-[(benzyloxy)carbonyl]-L-alanyl-L-alanine methyl ester 
• 16012-70-7 benzyloxycarbonyl-L-alanyl-L-alanine 
• 90303-02-9 Ala-PheCH₂Cl, HBr 
• 13585-98-3 N^α-benzyloxycarbobyl-L-alanyl-L-alanyl-L-alanine 

Relevant academic research and scientific papers

Thermitase - A Thermostable Serine Protease. II. Synthesis of Substrate Analogous Peptide Chloromethyl Ketones as Irreversibly Acting Inhibitors

The preparation of dipeptide to pentapeptide chloromethyl ketones of alanine with variation of the amino acid in the P1 and P2 position of the peptides is described.The synthesis is performed by fragment condensation of N-acylated amino acids or peptides with the unprotected chloromethyl ketone derivatives of amino acids and peptides, respectively.Some examples of enzyme inactivation by peptide chloromethyl ketones are discussed.