89614-97-1

Usage

Use in pharmaceutical industry

used as a starting material for the synthesis of various drugs and pharmaceuticals.

Use in biochemical research

used in biochemical research and found in some biochemical reagent kits.

HCl salt form

commonly used to increase the compound's solubility in water and aid in its stability.

Unique properties

due to its unique chemical structure and properties, 1-Methyl-L-proline HCl has a range of uses in the pharmaceutical and biochemical fields.

Upstream product

• 475-11-6 N-methyl-L-proline 
• 147-85-3 L-proline 

Downstream Products

• 1188422-69-6 rac-(3aR,14bR)-10-cyclohexyl-N₇-(dimethylsulfamoyl)-13-methoxy-N₃a,N₃a-dimethyl-2-(1-methyl-L-prolyl)-1,2,3,14b-tetrahydroindolo[2,1-a]pyrrolo[3,4-d][2]benzazepine-3a,7(4H)-dicarboxamide 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of novel stachydrine derivatives as potent neuroprotective agents for cerebral ischemic stroke

Stachydrine is a natural product with multiple protective biological activities, including those involved in preventing cancer, ischemia, and cardiovascular disease. However, its use has been limited by low bioavailability and unsatisfactory efficacy. To address this problem, a series of stachydrine derivatives (A1/A2/A3/A4/B1/B2/B3/B4) were designed and synthesized, and biological studies were carried out in vitro and in vivo. When compared with stachydrine, Compound B1 exhibited better neuroprotective effects in vitro, and significantly reduced infarction size in the model of the middle cerebral artery occlusion rat model. Therefore, Compound B1 was selected for further research on ischemic stroke. [Figure not available: see fulltext.].