89639-40-7Relevant academic research and scientific papers
Chloro-substituted 3-alkylamino-4h-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: Impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity
Pirotte, Bernard,De Tullio, Pascal,Nguyen, Quynh-Anh,Somers, Fabian,Fraikin, Pierre,Florence, Xavier,Wahl, Philip,Hansen, John Bondo,Lebrun, Philippe
experimental part, p. 147 - 154 (2010/05/18)
The synthesis of 5-chloro-, 6-chloro-, and 8-chloro-substituted 3-alkylamino/cycloalkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides is described. Their inhibitory effect on the insulin releasing process and their vasorelaxant activity was compared to that
