89656-83-7Relevant academic research and scientific papers
Michael reaction of acyclic β-enaminoesters derived from α-alkyl-β-ketoesters and chiral α-methylbenzylamine: Stereoselective generation of quaternary carbon centres
Maiti,Ghoshal,Mukhopadhyay,Achari,Banerjee
, p. 1072 - 1080 (2007/10/03)
Michael reaction of electrophilic olefins with acyclic β-enaminoester substrates derived from α-substituted β-ketoesters and (R)- or (S)-α-methylbenzylamine under neutral conditions resulted in the enantioselective formation of quaternary centres. The add
PREPARATION OF OPTICALLY ACTIVE TRICYCLIC 1,4-DIOXEPIN-5-ONE DERIVATIVES AND ITS APPLICATION TO ASYMMETRIC ALKYLATION
Kato, Keisuke,Suemune, Hiroshi,Sakai, Kiyoshi
, p. 413 - 424 (2007/10/02)
Chiral bicyclic α,β-unsaturated lactones (6a,b and 8a,b) were easily synthesized from chiral cyclic diols (2-4) and cyclic β-keto esters (1a,b).Alkylation of 8b proceeded in a highly diastereoselective manner to afford a quaternary carbon.
Asymmetric Alkylation Using Chiral Cyclic Diols to Prepare a Quaternary Carbon
Kato, Keisuke,Suemune, Hiroshi,Sakai, Kiyoshi
, p. 3315 - 3326 (2007/10/02)
Asymmetric alkylation of cyclic and acyclic β-keto ester acetals (4, 5, 13, 14, and 18) with C2-symmetric cycloalkane-1,2-dioxy moiety proceeded in a highly diastereoselective manner to afford enol ethers (9-12, 15-17, 19a-c) with a chiral quat
FACTORS CONTROLLING THE DIASTEREOFACE SELECTIVITY IN THE COMPLEMENTARY ASYMMETRIC ALKYLATION OF α-ALKYL β-KETO ESTERS
Tomioka, Kiyoshi,Ando, Kaori,Takemasa, Yutaka,Koga, Kenji
, p. 5677 - 5680 (2007/10/02)
Complementary asymmetric alkylation reaction of the lithioenamine derived from 2-methoxycarbonylcyclohexanone and (S)-valine tert-butyl ester was examined by employing the various electron pair donating additives in a toluene solvent, in order to clarify
