89671-77-2Relevant academic research and scientific papers
Palladium-catalyzed tandem oxidative annulation of α-amino ketones leading to 2-aroylindoles
Jiang, Tao-Shan,Dai, Long,Zhou, Yuhui,Zhang, Xiuli
, (2020/01/08)
A simple synthesis of 2-aroylindoles via palladium-catalyzed tandem oxidative annulation directly from α-amino ketones has been developed. In this transformation, two-step reaction including oxidation of α-amino aetones to generate imine intermediates and
Iodine-mediated intramolecular amination of ketones: The synthesis of 2-acylindoles and 2-acylindolines by tuning N-protecting groups
Gao, Wen-Chao,Jiang, Shan,Wang, Ruo-Lin,Zhang, Chi
supporting information, p. 4890 - 4892 (2013/07/05)
A general method for constructing both 2-acylindoles and 2-acylindolines via I2-mediated intramolecular C-N bond formation is presented, and the selective formation of either 2-acylindoles or 2-acylindolines just depends on the nitrogen protecting groups used in the same substrate skeletons. The Royal Society of Chemistry.
Palladium-catalyzed decarboxylative C2-acylation of indoles with α-oxocarboxylic acids
Pan, Changduo,Jin, Hongming,Liu, Xu,Cheng, Yixiang,Zhu, Chengjian
, p. 2933 - 2935 (2013/04/24)
A palladium-catalyzed decarboxylative C2-acylation of indoles with α-oxocarboxylic acids was achieved. This protocol represents a novel and complementary approach to 2-aroylindoles. The Royal Society of Chemistry 2013.
Synthesis of indoles through highly efficient cascade reactions of sulfur ylides and N-(ortho-chloromethyl)aryl amides
Yang, Qing-Qing,Xiao, Cong,Lu, Liang-Qiu,An, Jing,Tan, Fen,Li, Bin-Jie,Xiao, Wen-Jing
supporting information, p. 9137 - 9140 (2012/10/29)
Batting the ylides: A simple procedure carried out under mild conditions allows the direct and efficient synthesis of structurally diverse indoles. This approach involves a cascade reaction of sulfur ylides and N-(ortho-chloromethyl) aryl amides (see scheme). Copyright
SYNTHESIS OF 2-ACYLINDOLES FROM α-(N-ISATINYL) KETONES
Gorgos, V. I.,Zorin, L. M.,Zhungietu, G. I.,Rekhter, M. A.
, p. 1179 - 1181 (2007/10/02)
2-Acylindoles were synthesized by the recyclization of N-phenacyl- and N-acetonylisatins in alkaline medium and the decarboxylation of 2-acylindolyl-3-carboxylic acids or their salts in basic or neutral media.
