89671-78-3

Basic information

• Product Name: Methanone, (4-bromophenyl)-1H-indol-2-yl-
• CAS NO: 89671-78-3
• Molecular Formula: C15H10BrNO
• Molecular Weight: 300.154
• Mol File: 89671-78-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Methanone, (4-bromophenyl)-1H-indol-2-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-bromophenyl)-1H-indol-2-yl-(89671-78-3)
• EPA Substance Registry System: Methanone, (4-bromophenyl)-1H-indol-2-yl-(89671-78-3)

Safety Data

• Hazardous Substances Data: 89671-78-3(Hazardous Substances Data)

Upstream product

• 181867-44-7 C₁₅H₁₀BrNO₃ 
• 99-90-1 para-bromoacetophenone 
• 552-89-6 2-nitro-benzaldehyde 
• 823809-34-3 N-(2-aminobenzylidene)-4-methylaniline 
• 99-73-0 para-bromophenacyl bromide 
• 16714-25-3 2-azidobenzaldehyde 
• 75822-51-4 2-(4-Bromo-benzoyl)-1H-indole-3-carboxylic acid 
• 75822-43-4 1-(4-bromophenacyl)indole-2,3-dione 

Relevant articles and documents

Visible-light-driven Cadogan reaction

Visible-light-driven photochemical Cadogan-type cyclization has been discovered. The organic D-A type photosensitizer 4CzIPN found to be an efficient mediator to transfer energy from photons to the transient intermediate that breaks the barriers of deoxygenation in Cadogan reaction and enables a mild metal-free access to carbazoles and related heterocycles. DFT calculation results indicate mildly endergonic formation of the intermediate complex of nitrobiarenes and PPh3, which corresponds with experimental findings regarding reaction temperature. The robust synthetic capacity of the photoredox Cadogan reaction systems has been demonstrated by the viable productivity of a broad range of carbazoles and related N-heterocycles with good tolerance of various functionalities.

N-(2-Aminobenzylidene)-4-methylanilines - stable and cheap alternate for 2-aminobenzaldehydes: concise synthesis of 3-unsubstituted-2-aroylindoles

Abstract Synthesis of 3-unsubstituted-2-aroylindoles starting from readily available N-(2-aminobenzylidene)-4-methylanilines, cheap and stable alternative to 2-aminobenzaldehydes, and α-bromoketones was achieved in moderate to good yields under basic cond

SYNTHESIS OF 2-ACYLINDOLES FROM α-(N-ISATINYL) KETONES

2-Acylindoles were synthesized by the recyclization of N-phenacyl- and N-acetonylisatins in alkaline medium and the decarboxylation of 2-acylindolyl-3-carboxylic acids or their salts in basic or neutral media.