896746-89-7

Upstream product

• 204973-60-4 N-(9-fluorenylmethoxycarbonyl)-N’-methoxy-N’-methyl-L-isoasparagine t-butyl ester 
• 444608-34-8 C₉H₁₈N₄O₃ 
• 146803-45-4 N-(fluorenylmethyloxycarbonyl)-L-aspart-α-al β-tert-butyl ester 
• 71989-14-5 Fmoc-(tBu)Asp-OH 
• 896746-86-4 (R)-[3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetic acid ethyl ester 
• 896746-87-5 [(3R)-3-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]acetic acid 
• 896746-83-1 (R)-4-(2-benzoyl-phenylcarbamoyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 896746-85-3 (R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 896746-84-2 (R)-3-hydroxymethyl-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 
• 896746-88-6 3(R)-{2-[(3S)-(tert-butyldimethylsilanyloxymethyl)-2-oxo-5-phenyl-2,3-dihydrobenzo[e][1,4]diazepin-1-yl]acetylamino}-4-samicarbazone-butyric acid tert-butyl ester 

Downstream Products

• 896746-96-6 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(2-bromo-4,6-difluorophenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-98-8 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(4-chloro-2-trifluoromethylphenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-93-3 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(4-chlorophenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-91-1 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(1-naphthylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-95-5 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(2,4-difluorophenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-97-7 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(4-chloro-2-methylphenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-92-2 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(4-methoxyphenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-94-4 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(4-fluorophenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 
• 896746-90-0 4-semicarbazone-3(S)-[2-(2-oxo-5-phenyl-3(R)-(phenylcarbamoyloxymethyl)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl)acetylamino]butyric acid tert-butyl ester 

Relevant academic research and scientific papers

Novel peptidomimetic cysteine protease inhibitors as potential antimalarial agents

The synthesis of a new class of peptidomimetics 1a-j, based on a 1,4-benzodiazepine scaffold and on a C-terminal aspartyl aldehyde building block, is described. Compounds 1a-j provided significant inhibitory activity against falcipains 2A and 2B (FP-2A an