89694-28-0Relevant academic research and scientific papers
CYCLIC INHIBITORS OF HEPATITIS B VIRUS
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Page/Page column 72; 98, (2020/02/14)
The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alone or in combination with other agents for treating, ameliorating, preventing or curing HBV infection and related conditions. The present invention also relates to pharmaceutical compositions containing said compounds.
Effect of C7 Modifications on Benzothiadiazine-1,1-dioxide Derivatives on Their Inhibitory Activity and Selectivity toward Aldose Reductase
Zhang, Shuzhen,Chen, Xin,Parveen, Shagufta,Hussain, Saghir,Yang, Yanchun,Jing, Chaojun,Zhu, Changjin
, p. 603 - 613 (2013/08/22)
The development and progression of chronic complications in diabetic patients, such as retinopathy, nephropathy, neuropathy, cataracts, and stroke, are related to the activation and/or overexpression of aldose reductase (ALR2), which is a member of the al
Effect on KATP channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides
Boverie, Stéphane,Antoine, Marie-Hélène,Somers, Fabian,Becker, Bénédicte,Sebille, Sophie,Ouedraogo, Raogo,Counerotte, Stéphane,Pirotte, Bernard,Lebrun, Philippe,De Tullio, Pascal
, p. 3492 - 3503 (2007/10/03)
The present work explored 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides diversely substituted in the 7-position. Those compounds, structurally related to previously described potassium channel openers such as the benzothiadiazine dioxide BPDZ 73, we
1,2,4-benzothiadiazine derivatives, their preparation and use
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, (2008/06/13)
1,2,4-Benzothiadiazine derivatives represented by formula wherein D, R1, R2, R3, R4, R5, R12, R13, R14, R15 are defined in the description, composition thereof and methods for preparing the compounds are described.The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system.
