89717-68-0

Usage

Structure

A derivative of the pyrazole ring with a bromine atom at the 4 position, a methoxy group at the 5 position, and a methyl group at the 1 position.

Type of compound

A chemical compound

Potential applications

Organic synthesis and medicinal chemistry, used as a building block in the synthesis of various pharmaceuticals and other organic compounds.

Specific properties and potential uses

Of interest for researchers and chemists.

Upstream product

• 124-41-4 sodium methylate 
• 89607-11-4 4-bromo-1-methyl-5-nitropyrazole 
• 1350323-88-4 5-methoxy-1-methyl-1H-pyrazole 

Downstream Products

• 1350323-87-3 3-[(1S)-1-(2-chloro-3-fluoro-6-methoxyphenyl)ethyl]-5-(5-methoxy-1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine 

Relevant academic research and scientific papers

Fused Bicyclic Kinase Inhibitors

Compounds of Formula I, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by at least one of RON, MET or ALK. This Abstract is not limiting of the invention.

Cyclic Meso-ionic Compounds. Part 21. The Examination of Nitro-derivatives of Meso-ionic Heterocycles as Potential Pharmaceuticals

The synthesis of nitro-substituted meso-ionic compounds has been examined in an attempt to obtain analogues of the biologically active heterocycles (1)-(3).The synthesis of the compounds (4) and (5) has been achieved but their instability precluded biological evaluation.The synthesis of the type-B meso-ionic heterocycle (6) was not successfully completed, but unusual nucleophilic displacement reactions of the pyrazole (13) -> (16) + (17) and the pyrazolium salt (14) -> (15) are reported.