89720-77-4

Basic information

• Product Name: 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE
• Synonyms: 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE
• CAS NO: 89720-77-4
• Molecular Formula: C₇H₅Br₂Cl
• Molecular Weight: 284.3756
• EINECS: -0
• Product Categories: Aromatics;Intermediates
• Mol File: 89720-77-4.mol
• Article Data: 28

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE(89720-77-4)
• EPA Substance Registry System: 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE(89720-77-4)

Safety Data

• RIDADR: 3265
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 89720-77-4(Hazardous Substances Data)

Usage

Uses

4-Bromo-1-bromomethyl-2-chlorobenzene is used in the preparation of selective aldose reductase inhibitors.

Upstream product

• 185312-82-7 4-bromo-2-chlorobenzoic acid methyl ester 
• 59748-90-2 4-Bromo-2-chloro-benzoic Acid 
• 158435-41-7 4-bromo-2-chlorobenzaldehyde 
• 185315-48-4 (4-bromo-2-chlorophenyl)methanol 
• 151-50-8 potassium cyanide 
• 89794-02-5 4-bromo-2-chlorotoluene 

Downstream Products

• 67197-54-0 2-(4-bromo-2-chlorophenyl)acetonitrile 
• 1213929-66-8 C₉H₉BrClNO₂ 
• 1432502-36-7 C₁₄H₁₇BrClNO₄ 
• 1432502-37-8 C₂₀H₂₃BrClNO₇ 
• 1432502-38-9 C₂₀H₂₅BrClNO₆ 
• 1432502-39-0 C₁₆H₁₉BrClNO₃ 
• 1432502-40-3 C₁₁H₁₁BrClNO 
• 1432502-41-4 C₁₆H₁₉BrClNO₂ 
• 1432502-42-5 C₁₆H₁₉BrClNO₃ 
• 1432502-43-6 C₁₁H₁₃BrClNO₃*ClH 
• 1432502-44-7 (2R,4R)-4-amino-5-(4-bromo-2-chlorophenyl)-2-hydroxypentanoic acid ethyl ester hydrochloride 
• 1428758-45-5 C₂₉H₂₉ClN₈O 
• 1330065-78-5 C₃₀H₃₀ClN₇OS 
• 1428760-83-1 3-chloro-4-(8-ethyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)benzonitrile 

Relevant articles and documents

HISTONE METHYLTRANSFERASE EZH2 INHIBITOR, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF

The invention relates to a histone methyltransferase EZH2 inhibitor, a preparation method and pharmaceutical use thereof. In particular, the invention relates to a compound represented by the general formula (I), a preparation method thereof, a pharmaceut

SERINE/THREONINE KINASE INHIBITORS

Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula (I): where R1-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.