89721-07-3Relevant academic research and scientific papers
ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
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Paragraph 0167-0169, (2019/11/19)
A compound having the formula Ir(LA)(LB), where LA has a structure of Formula I and LB is a bidentate ligand is disclosed. In the structure of Formula I, rings A, B, C, and D are each independently 5- or 6-membe
Selective and Serial Suzuki-Miyaura Reactions of Polychlorinated Aromatics with Alkyl Pinacol Boronic Esters
Laulhé, Sébastien,Blackburn, J. Miles,Roizen, Jennifer L.
supporting information, p. 4440 - 4443 (2016/09/09)
Among cross-coupling reactions, the Suzuki-Miyaura transformation stands out because of its practical advantages, including the commercial availability and low toxicity of the required reagents, mild reaction conditions, and functional group compatibility. Nevertheless, few conditions can be used to cross-couple alkyl boronic acids or esters with aryl halides, especially 2-pyridyl halides. Herein, we describe two novel Suzuki-Miyaura protocols that enable selective conversion of polychlorinated aromatics, with a focus on reactions to convert 2,6-dichloropyridines to 2-chloro-6-alkylpyridines or 2-aryl-6-alkylpyridines.
Chemoselective chromium(II)-catalyzed cross-coupling reactions of dichlorinated heteroaromatics with functionalized aryl Grignard reagents
Steib, Andreas K.,Kuzmina, Olesya M.,Fernandez, Sarah,Malhotra, Sushant,Knochel, Paul
supporting information, p. 1961 - 1965 (2015/01/30)
Chromium(II) chloride catalyzes the chemoselective cross-coupling reaction of dichloropyridines with a range of functionalized (hetero)aromatic Grignard reagents at room temperature. Functional groups, such as esters and acetals, are well tolerated in this transformation. Previously challenging substrates, quinolines and isoquinolines, participate in the selective Cr-catalyzed cross-coupling in cyclopentyl methyl ether (CPME) as the solvent. The effective purging of Cr salts is demonstrated by using various solid supports.
Exploitation of differential reactivity of the carbon-chlorine bonds in 1,3-dichloroisoquinoline. Routes to new N,N-chelate ligands and 1,3-disubstituted isoquinolines
Ford, Alan,Sinn, Ekkehard,Woodward, Simon
, p. 927 - 934 (2007/10/03)
Under Pd(PPh3)4 catalysis, coupling of arylboronic acids to the 1-position of 1,3-dichloroisoquinoline takes place, leading exclusively to 1-aryl-3-chloroisoquinolines. This regiochemistry is demonstrated by the crystal structure of
