89722-92-9Relevant academic research and scientific papers
AMIDINES. PART XXII. BASICITY OF N1,N1-DIMETHYLBENZAMIDINES, p-CHLOROBENZAMIDINES AND p-METHYLBENZAMIDINES
Oszczapowicz, Janusz,Krawczyk, Waldemar,Osek, Jerzy,Raczynska, Ewa
, p. 157 - 162 (2007/10/02)
Three series of N1,N1-dimethylbenzamidines,each containing the same set of 12 variable substituents at imino nitrogen atom, have been synthesized and their pKa values in 95.6percent ethanol (azeotrope) determined.Their pKavalues have been correlated with ? and ?0 values as well as with the pKa values of corresponding primary amines.It was found that the ρ values for the series are indistinguishable within confidence intervals,but are undoubtedly different from the ρ value of N1,N1-dimethylformamidines.This provides a support for an earlier conclusion that the sensitivity of the amidino group to substitution at the imino nitrogen atom depends to a considerable degree on substitution at the amidino carbon atom.
Cycloaddition of Diphenylcyclopropenone with Carboximidate, Carboximidamide, and Carboximidothioate
Yoshida, Hiroshi,Sogame, Shingo,Bando, Shoichi,Nakajima, Shosuke,Ogata, Tsuyoshi,Matsumoto, Kiyoshi
, p. 3849 - 3850 (2007/10/02)
The reaction of diphenylcyclopropenone with R1N=C(R2)X (2) (R1, R2=alkyl, aryl, X=MeO, EtO, MeS, or Me2N) gave 2-pyrrolin-4-one (3) in good yield.The less reactive carboximidothioate (2, R1=4-MeC6H4, R2=Ph, X=MeS) yielded isomeric 3-pyrrolin-2-one together with 3.
