897384-05-3

Upstream product

• 162012-69-3 7-fluoro-6-nitro-3H-quinazolin-4-one 
• 1012057-47-4 7-methoxy-6-nitroquinazolin-4(3H)-one 
• 55496-69-0 4-chloro-7-methoxy-6-nitroquinazoline 
• 1194097-41-0 2-amino-4-fluoro-5-nitrobenzoic acid 
• 897384-03-1 N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine 

Relevant academic research and scientific papers

Discovery of a novel Her-1/Her-2 dual tyrosine kinase inhibitor for the treatment of Her-1 selective inhibitor-resistant non-small cell lung cancer

A novel series of (S)-1-acryloyl-N-[4-(arylamino)-7-(alkoxy)quinazolin-6- yl]pyrrolidine-2-carboxamides were synthesized and evaluated as Her-1/Her-2 dual inhibitors. In contrast to the Her-1 selective inhibitors, our novel compounds are irreversible inhi

QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF

The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof for inhibiting the growth of cancer cells, a method for the preparation thereof and a pharmaceutical composition comprising same as an active ingredient.