897440-34-5

Upstream product

• 151-50-8 potassium cyanide 
• 25662-24-2 N-benzyl-2-(bromomethyl)aziridine 

Downstream Products

• 897440-42-5 4-chloro-3-(N-chloro-N-(dichloro(phenyl)methyl)amino)butanenitrile 
• 942915-22-2 4-[N-benzyl-N-(4-bromobenzyl)amino]-3-bromobutanenitrile 
• 137428-38-7 (2Z)-4-(N,N-dibenzylamino)-2-butenenitrile 
• 137428-39-8 (2E)-4-(N,N-dibenzylamino)-2-butenenitrile 
• 942915-21-1 4-(N,N-dibenzylamino)-3-bromobutanenitrile 
• 1170322-80-1 (E)-3-(benzylideneamino)-4-bromobutanenitrile 
• 1227663-73-1 4-bromo-3-[N-(phenylmethyl)amino]butanenitrile 

Relevant academic research and scientific papers

Synthesis of 2-[(arylmethylene)amino]cyclopropanecarbonitriles via a two-step ring transformation of 2-(cyanomethyl)aziridines

Reaction of 2-(cyanomethyl)aziridines with N-bromosuccinimide in dichloromethane results in the formation of 3-[(arylmethylene) amino]-4-bromobutanenitriles in high yield. The latter α-amino-γ- bromobutanenitriles were converted into separable trans- and

Synthesis of 1-arylmethyl-2-(cyanomethyl)aziridines and their ring transformation into methyl N-(2-cyanocyclopropyl)benzimidates

1-Arylmethyl-2-(cyanomethyl)aziridines were prepared in high yields from the corresponding 2-(bromomethyl)aziridines upon treatment with potassium cyanide in DMSO. Ring opening of the aziridine moiety with N-chlorosuccinimide in CCL4 and subseq