897446-12-7

Usage

Uses

Used in Organic Synthesis:
3-[(tert-butoxycarbonyl)amino]pyrrolidin-1-yl(phenyl)acetic acid is used as a building block in organic synthesis for the creation of other complex molecules. Its diverse functional groups allow for a wide range of chemical reactions and modifications, making it a versatile component in the synthesis of various compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-[(tert-butoxycarbonyl)amino]pyrrolidin-1-yl(phenyl)acetic acid is used as a potential candidate for drug development. Its unique structure and functional groups may contribute to the design and synthesis of new drugs with specific therapeutic properties. The molecule's potential applications in this field would depend on the context and specific research goals.
Used in Chemical Research:
3-[(tert-butoxycarbonyl)amino]pyrrolidin-1-yl(phenyl)acetic acid is also utilized in chemical research to study the properties and reactivity of its various functional groups. This can lead to a better understanding of the molecule's behavior in different chemical environments and may contribute to the development of new synthetic methods or applications in other industries.

Upstream product

• 99724-19-3 3-(tert-butoxycarbonylamino)pyrrolidine 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 850418-40-5 (3-tert-butoxycarbonylamino-pyrrolidin-1-yl)-phenyl-acetic acid methyl ester 
• 298-12-4 Glyoxilic acid 
• 98-80-6 phenylboronic acid 

Downstream Products

• 897446-42-3 (1-{[(2-aminophenyl)carbamoyl](phenyl)methyl}pyrrolidin-3-yl)carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

Design, synthesis and structure-activity relationships of benzimidazole derivatives as activators of the AMP-activated protein kinase (AMPK) are presented in this paper. AMPK is the central component of a protein kinase cascade that plays a key role in the regulation of energy balance. Once activated, AMPK initiates a series of responses that are aimed at restoring the energy balance of the cell and recent studies have indicated that AMPK plays an important role in regulation of the whole-body energy metabolism. The following study based on the lead compound S27847 involved modification of three regions of this compound. Preliminary structure-activity relationships are being described.

Diastereoselective Petasis Mannich reactions accelerated by hexafluoroisopropanol: A pyrrolidine-derived arylglycine synthesis

A diastereoselective synthesis of pyrrolidine-derived arylglycines has been developed using the Petasis boronic acid Mannich reaction. High diastereoselectivities in the reactions of chiral amines, aryl boronic acids, and glyoxylic acid monohydrate have been demonstrated for the first time. Key to the implementation of this method is the discovery that hexafluoroisopropanol accelerates the Petasis process, reducing reaction times from multiple days to less than 24 h.