99724-19-3

Usage

Uses

Used in Pharmaceutical Synthesis:
3-N-Boc-aminopyrrolidine is used as a key intermediate in the synthesis of chiral compounds for pharmaceutical applications. Its unique structure and reactivity make it a valuable component in the creation of new drugs and therapeutic agents.
Used in Peptide Synthesis:
3-N-Boc-aminopyrrolidine is used as a reactant in the synthesis of peptides, specifically in the development of peptide-based drugs and therapeutic agents. Its ability to form stable peptide bonds contributes to the overall stability and effectiveness of the final peptide product.
Used in G-Protein Coupled Receptors Test:
3-N-Boc-aminopyrrolidine is used as a reactant in the peptide activated G-protein coupled receptors test. This test is crucial in evaluating the interaction between peptides and G-protein coupled receptors, which play a significant role in cellular signaling and various physiological processes.

InChI:InChI=1/C9H18N2O2/c1-9(2,3)13-8(12)11-7-4-5-10-6-7/h7,10H,4-6H2,1-3H3,(H,11,12)/p+1/t7-/m0/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 79286-79-6 (3S)-3-aminopyrrolidine 
• 99735-30-5 N-benzyl-3-(R)-((1,1-dimethylethoxycarbonyl)amino)pyrrolidine 

Downstream Products

• 391903-23-4 N-[1-(3-Amino-4-nitrophenyl)pyrrolidin-3-yl] (tert-butoxy)carboxamide 
• 635309-36-3 ethyl 7-(3-((tert-butoxycarbonyl)amino)pyrrolidin-1-yl)-1-(2,4-dimethoxybenzyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate 
• 226248-99-3 3-{(tert-butoxycarbonyl)amino}-1-(4-chlorobenzyl)-pyrrolidine 
• 828928-31-0 [1-(2,2-diphenylethyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 
• 897446-12-7 {3-[(tert-butoxycarbonyl)amino]pyrrolidin-1-yl}(phenyl)acetic acid 
• 850418-40-5 (3-tert-butoxycarbonylamino-pyrrolidin-1-yl)-phenyl-acetic acid methyl ester 
• 172414-99-2 4-(3-tert-butoxycarbonylamino-pyrrolidin-1-yl)-2,3,5,6-tetrafluoro-benzoic acid ethyl ester 
• 956460-21-2 tert-butyl 1-{4-[4-(aminocarbonyl)-1H-benzimidazol-2-yl]benzyl}pyrrolidin-3-ylcarbamate 
• 1013111-68-6 tert-butyl (1-(2-amino-6-[(E)-2-phenylvinyl]pyrimidin-4-yl)pyrrolidin-3-yl)carbamate 
• 1013112-15-6 tert-butyl (1-[2-amino-6-(cyclohexylmethyl)pyrimidin-4-yl]pyrrolidin-3-yl)carbamate formate 
• 330551-18-3 [1-(4-aminophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester 
• 850628-92-1 {1-[4-(8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)phenyl]pyrrolidin-3-yl}carbamic acid tert-butyl ester 
• 684287-55-6 C₄₁H₃₉FN₄O₆ 
• 816424-94-9 rac-tert-butyl [1-({3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridin-2-yl}carbonyl)pyrrolidin-3-yl]carbamate 

Relevant academic research and scientific papers

NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention discloses novel naphthalenyloxypropenyl derivatives useful for inhibiting the enzyme activity of histone deacetylase, leading effective suppression of cancer cell proliferation

ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF

This invention discloses a novel alkylcarbamoyl naphthalenyloxy octenoylhydroxyamide derivative of formula (1) useful for inhibiting the enzyme activity of histone deacetylase, which leads to effective suppression of the cancer cell proliferation, a method for preparing same and a pharmaceutical composition comprising same.

PROCESS FOR PRODUCING 1-ALKOXYCARBONYL NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE

A method for producing N-protected heterocyclic compounds such as 1-alkoxycarbonyl-3-aminopyrrolidines through position-selective reaction at the nitrogen atom that constitutes the hetero ring of a nitrogen-containing saturated heterocyclic compound having two nitrogen atoms such as 3-aminopyrrolidine. A dialkyl dicarbonate (ROCO-O-COOR) is reacted with a nitrogen-containing saturated heterocyclic compounds having two nitrogen atoms, at pH of from 9 to 14 to obtain a high-purity 1-alkoxycarbonyl nitrogen-containing saturated heterocyclic compound.

2-aminopyridine derivatives and combinatorial libraries thereof

The present invention relates to novel 2-aminopyridine derivative compounds of the following formula: wherein R1to R5have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminopyridine derivative compounds.

Naphthyridine antibacterial agents

Novel naphthyridine-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.

Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic acid

An improved process for the preparation of 3-chloro-2,4,5-trifluorobenzoic acid is described which involves reaction of a diester of 3,4,5,6-tetrafluoro-1,2-benzenedicarboxylic acid with a substituted amine to afford 3-amino-2,4,5-trifluorobenzoic acid followed by subsequent conversion of the amio intermediate into 3-chloro-2,4,5-trifluorobenzoic acid.

4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents

Novel naphthyridine-, quinoline- and benzoxazinecarboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the manufacture of the antibacterial agents.

Antibacterial agents

Novel naphthyridine-, quinoline- and benzoxazine-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the manufacture of the antibacterial agents.

Antibacterial agents III

Novel 1-amino-naphthyridine- and quinoline-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.

7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents

Novel 1-aryl or heteroaryl-6,8-difluoro-1,4-dihydro-7-(3-aminomethyl)pyrrolidinyl- or 7-spiroamino-4-oxo-3-quinolinecarboxylic acids and acid derivatives thereof as antibacterial agents are described as well as methods for their manufacture, formulation a