897664-60-7

Upstream product

• 444196-21-8 16-hydroxymethylene-3-benzyloxyestra-1,3,5⁽¹⁰⁾-trien-17-one 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 897664-64-1 17-(benzothien-2'-yl)-3-benzyloxy-16-formyl-estra-1,3,5⁽¹⁰⁾,16-tetraene 
• 897664-71-0 17-(benzothien-2'-yl)-3-benzyloxy-16-(2'',2''-dibromoethenyl)-estra-1,3,5⁽¹⁰⁾,16-tetraene 
• 897664-75-4 3-benzyloxy-16-ethynyl-17-(benzothien-2'-yl)-estra-1,3,5⁽¹⁰⁾,16-tetraene 
• 897664-70-9 3-benzyloxy-16-(2',2'-dibromoethenyl)-17-(thien-2''-yl)-estra-1,3,5⁽¹⁰⁾,16-tetraene 
• 897664-74-3 3-benzyloxy-16-ethynyl-17-(thien-2'-yl)-estra-1,3,5⁽¹⁰⁾,16-tetraene 
• 897664-63-0 3-benzyloxy-16-formyl-17-(2-thienyl)-estra-1,3,5⁽¹⁰⁾,16-tetraene 

Relevant academic research and scientific papers

Benzothieno and benzofurano annelated estranes

The preparation of estrone derived benzothieno- and benzofurano fused steroids is described. Keystep is an intramolecular thienyl(/furyl)-ene-yne cyclization of 16-ethynyl-17-heterarylestra-1,3,5(10),16-tetraenes. The cyclization was carried out under Pt as well as under Ru catalysis.