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5-Amino-2-cyano-4-methylpyridine is a pyridine derivative with the molecular formula C7H6N3. It features a cyano group and an amino group attached to the 2 and 5 positions of the pyridine ring, respectively. This chemical compound is widely recognized for its role as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as for its potential biological and pharmacological activities.

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  • 897733-08-3 Structure
  • Basic information

    1. Product Name: 5-AMino-2-cyano-4-Methylpyridine
    2. Synonyms: 5-AMino-2-cyano-4-Methylpyridine;5-amino-4-methyl-2-pyridinecarbonitrile;5-Amino-4-methyl-pyridine-2-carbonitrile
    3. CAS NO:897733-08-3
    4. Molecular Formula: C7H7N3
    5. Molecular Weight: 133.15058
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 897733-08-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-AMino-2-cyano-4-Methylpyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-AMino-2-cyano-4-Methylpyridine(897733-08-3)
    11. EPA Substance Registry System: 5-AMino-2-cyano-4-Methylpyridine(897733-08-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 897733-08-3(Hazardous Substances Data)

897733-08-3 Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
5-Amino-2-cyano-4-methylpyridine is used as a key building block for the development of various pharmaceuticals and agrochemicals. Its unique structure allows for the creation of a broad range of compounds with diverse therapeutic and pesticidal properties.
Used in Pyridine-Containing Ligand Preparation:
In the field of transition metal-catalyzed reactions, 5-amino-2-cyano-4-methylpyridine is utilized in the preparation of pyridine-containing ligands. These ligands are essential for enhancing the efficiency and selectivity of various catalytic processes.
Used in Organic Synthesis:
This chemical compound is also employed in organic synthesis, where it serves as a versatile intermediate for the construction of complex organic molecules. Its reactivity and functional group compatibility make it a valuable component in the synthesis of a wide array of organic compounds.
Used in Biological and Pharmacological Research:
5-Amino-2-cyano-4-methylpyridine has been studied for its potential biological and pharmacological activities. It has shown promise as a potential inhibitor of certain enzymes, which could lead to the development of new therapeutic agents for various diseases.
Overall, 5-amino-2-cyano-4-methylpyridine is a multifaceted chemical compound with applications spanning across pharmaceuticals, agrochemicals, organic synthesis, and biological research. Its versatility and potential for further development make it an important compound in the fields of chemistry and life sciences.

Check Digit Verification of cas no

The CAS Registry Mumber 897733-08-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,7,7,3 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 897733-08:
(8*8)+(7*9)+(6*7)+(5*7)+(4*3)+(3*3)+(2*0)+(1*8)=233
233 % 10 = 3
So 897733-08-3 is a valid CAS Registry Number.

897733-08-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-amino-4-methylpyridine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names 5-AMINO-4-METHYLPICOLINONITRILE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:897733-08-3 SDS

897733-08-3Downstream Products

897733-08-3Relevant articles and documents

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

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Paragraph 0278, (2019/05/10)

The present invention discloses compounds according to Formula I: (Formula I) Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein. The present invention relates to compounds, met

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

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Paragraph 0733, (2017/02/09)

The present invention discloses compounds according to Formula (I), wherein R1, R3, R4, R5, L1, and Cy are as defined herein. The present invention also provides compounds, methods for the production of said compounds of the invention, pharmaceutical compositions comprising the same and their use in allergic or inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 and/or interferons. The present invention also methods for the prevention and/or treatment of the aforementioned diseases by administering a compound of the invention.

Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

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Page/Page column 55; 56; 81; 82, (2017/01/09)

The present invention discloses compounds according to Formula I: wherein Cy, R1, L1, R3, R4, R5, La, and Ra are as defined herein. Novel benzimidazoles according to Formula I, a

BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

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, (2015/08/06)

The present invention discloses compounds according to Formula (I) wherein Cy, R1, L1 R3, R4, R5, La, and Ra are as defined herein. Novel benzimidazoles according to Formula (I),

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

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Paragraph 0437-0440; 0535, (2015/07/27)

The present invention discloses compounds according to Formula I: wherein Cy, R1, L1, R3, R4, R5, La, and Ra are as defined herein. Novel benzimidazoles according to Formula I, a

NITROGENATED FUSED RING DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE OF THE SAME FOR MEDICAL PURPOSES

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Page/Page column 26, (2010/01/29)

[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution] The present invention provides nitrogen-containing fused ring derivatives represented by the following general formula (I) which has a GnRH antagonistic activity, prodrugs, salts, pharmaceutical compositions containing the same, medicinal uses thereof and the like. In the formula (I), rings A and B are independently aryl or heteroaryl; RA and RB are independently halogen, cyano, alkyl, alkylsulfonyl, -OW1, -SW1, -COW2, -NW3W4, -SO2NW3W4, aryl, etc.; RC is H or alkyl; E is oxygen atom, etc.; U is single bond or alkylene; and X is Y, -CO-Y, -SO2-Y -S-(alkylene)-Y, -O-(alkylene)-Y, -SO2-(alkylene)-Y, etc.; Y is Z or amino, etc.; and Z is cycloalkyl, heterocycloalkyl, aryl, heteroaryl, etc.

Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto

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Page/Page column 66, (2008/06/13)

The present invention relates to certain substituted pyridinyl and pyrimidinyl derivatives of Fomula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and com

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