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CAS

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897769-55-0

7-chloro-3-(2-methoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 897769-55-0 Structure

  • Basic information

    1. Product Name: 7-chloro-3-(2-methoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine
    2. Synonyms:
    3. CAS NO:897769-55-0
    4. Molecular Formula:
    5. Molecular Weight: 287.749
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 897769-55-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-chloro-3-(2-methoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-chloro-3-(2-methoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine(897769-55-0)
    11. EPA Substance Registry System: 7-chloro-3-(2-methoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine(897769-55-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 897769-55-0(Hazardous Substances Data)

897769-55-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 897769-55-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,7,7,6 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 897769-55:
(8*8)+(7*9)+(6*7)+(5*7)+(4*6)+(3*9)+(2*5)+(1*5)=270
270 % 10 = 0
So 897769-55-0 is a valid CAS Registry Number.

897769-55-0Downstream Products

897769-55-0Relevant articles and documents

Optimization of 3-phenylpyrazolo[1,5-a]pyrimidines as potent corticotropin-releasing factor-1 antagonists with adequate lipophilicity and water solubility

Chen, Chen,Wilcoxen, Keith M.,Huang, Charles Q.,McCarthy, James R.,Chen, Takung,Grigoriadis, Dimitri E.

, p. 3669 - 3673 (2007/10/03)

In our efforts to identify potent CRF1 antagonists with proper physicochemical properties, a series of 3-phenylpyrazolo[1,5-a]pyrimidines bearing polar groups, such as amino, hydroxyl, methoxy, sulfoxide, were designed and synthesized. Several positions of the core structure were identified, where a polar group was tolerated with slight reduction in receptor binding. NBI 30545 (18n) was found to have good binding affinity and potent antagonistic activity at the human CRF1 receptor. Moreover, this compound had proper lipophilicity (logD=2.78) and good solubility in water (>10mg/mL), and exhibited good plasma and brain exposure when given orally.

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