89784-02-1 Usage
Uses
Used in Agricultural Pest Control:
2-AMINO-4-CHLORO-6-ETHOXYPYRIMIDINE is used as an insecticide and acaricide for controlling pests on crops such as cotton, soybeans, and tobacco. It is applied to target a wide range of insects and mites, protecting the crops from damage and ensuring a healthy yield.
The use of acephate in agriculture is favored due to its relatively low toxicity to birds and its non-persistence in the environment, which minimizes the risk of long-term ecological impact. However, it is crucial to handle and apply this chemical with care to prevent potential harm to humans and other mammals.
Check Digit Verification of cas no
The CAS Registry Mumber 89784-02-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,7,8 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89784-02:
(7*8)+(6*9)+(5*7)+(4*8)+(3*4)+(2*0)+(1*2)=191
191 % 10 = 1
So 89784-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H8ClN3O/c1-2-11-5-3-4(7)9-6(8)10-5/h3H,2H2,1H3,(H2,8,9,10)
89784-02-1Relevant academic research and scientific papers
Development of the Late-Phase Manufacturing Process of ZPL389: Control of Process Impurities by Enhanced Process Knowledge
Santandrea, Ernesto,Waldraff, Christine,Gerber, Gilles,Moreau, Ma?l,Beney, Pascal
supporting information, p. 1190 - 1205 (2021/05/06)
The development of the late-phase manufacturing process of the drug candidate ZPL389 and the strategies for the control of impurities are outlined in detail. Selective salt formation at several stages was pivotal to controlling the process impurities. The extensive optimization of the N-methylation of a Boc-protected amine with dimethyl sulfate and of a nucleophilic aromatic substitution without the use of metal catalysts led to a robust, scalable process. The process was demonstrated on a >100 kg scale. Overall, improved drug substance quality, higher yield, and reduction of the process mass intensity were achieved.
