89791-03-7

Basic information

• Product Name: 3,4-diaMino-N,N-diethyl-BenzaMide
• Synonyms: 3,4-diaMino-N,N-diethyl-BenzaMide
• CAS NO: 89791-03-7
• Molecular Formula: C₁₁H₁₇N₃O
• Molecular Weight: 207.27218
• Mol File: 89791-03-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-diaMino-N,N-diethyl-BenzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diaMino-N,N-diethyl-BenzaMide(89791-03-7)
• EPA Substance Registry System: 3,4-diaMino-N,N-diethyl-BenzaMide(89791-03-7)

Safety Data

• Hazardous Substances Data: 89791-03-7(Hazardous Substances Data)

Upstream product

• 89790-82-9 4-Amino-N,N-diethyl-3-nitro-benzamide 
• 89790-61-4 2'-Nitro-4'-diethylcarbamoyl-acetanilid 
• 1539-06-6 3-nitro-4-acetamidobenzoic acid 
• 556-08-1 p-(acetylamino)benzoic acid 
• 24170-23-8 3-nitro-4-acetylaminobenzoyl chloride 

Relevant articles and documents

Amino-benzoic acids and derivatives, and methods of use

The present invention relates to compounds, compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with a carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.

Methods for glycosylation inhibition using amino-benzoic acids and derivatives

The present invention relates to compounds, compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with a carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.

Syntheses and anthelmintic activity of alkyl 5(6)-(substituted-carbamoyl)- and 5(6)-(disubstituted-carbamoyl)benzimidazole-2-carbamates and related compounds

A number of alkyl 5(6)-(sustituted-carbamoyl)- and 5(6)-(disubstituted-carbamoyl)benzimidazole-2-carbamates and related compounds have been synthesized, and their anthelmintic activity against various intestinal helminths of experimental animals have been evaluated. A large percentage of the compounds synthesized showed noteworthy activity against Ancylostoma ceylanicum and at higher doses against Hymenolepsis nana infections. Compared to the alkyl 5(6)-(substituted-carbamoyl)benzimidazole-2-carbamates, the disubstituted carbamoyl analogues were found to exhibit better anthelmintic activity. The most active compound of the series, namely, methyl 5(6)-[(N-2- pyridylpiperazino)carbamoyl]benzimidazole-2-carbamate (90), has been screened against intestinal helminths in higher animals and as a micro- and macrofilaricidal agent. Compound 90 has been identified as a broad-spectrum anthelmintic agent. Compound 90 has been identified as a broad-spectrum anthelmintic in view of its efficacy against A. ceylanicum (hamsters and dogs), H. nana (rats), Nippostrongylus brasiliensis (rats), Syphacia obvelata (mice), A. tubaeformis (cat), Toxocara spp. (cat), and Litomososoides carinii (cotton rat).