89794-15-0

Basic information

• Product Name: 2-AMino-6-(broMoMethyl)-4(3H)-pteridinone
• Synonyms: 2-AMino-6-(broMoMethyl)-4(3H)-pteridinone
• CAS NO: 89794-15-0
• Molecular Formula: C₇H₆BrN₅O
• Molecular Weight: 256.05944
• Product Categories: Aromatics, Inhibitors, Nucleotides, Bases & Related Reagents
• Mol File: 89794-15-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMino-6-(broMoMethyl)-4(3H)-pteridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMino-6-(broMoMethyl)-4(3H)-pteridinone(89794-15-0)
• EPA Substance Registry System: 2-AMino-6-(broMoMethyl)-4(3H)-pteridinone(89794-15-0)

Safety Data

• Hazardous Substances Data: 89794-15-0(Hazardous Substances Data)

Usage

Chemical Properties

Brown Solid

Uses

2-Amino-6-(bromomethyl)-4(3H)-pteridinone is a reactant used in the preparation of bisubstrate analog inhibitors of hydroxymethyl dihydropterin pyrophosphokinase.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 24, p. 279, 1987 DOI: 10.1002/jhet.5570240154

Upstream product

• 37150-52-0 3-bromoacetonaldoxime 

Downstream Products

• 59-30-3 (S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)pentanedioic acid 
• 59-05-2 N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid 

Relevant articles and documents

Folic acid synthesis method

The present invention relates to a folic acid synthesis method. According to the present invention, with the method, a 2,4,5-triamino-6-hydroxypyrimidine salt, 3-halogenated pyruvaldehyde oxime and N-(4-aminobenzamide)-L-glutamic acid are subjected to a reaction to prepare the folic acid; and the 3-halogenated pyruvaldehyde oxime is used to replace the low purity 1,1,3-trichloroacetone, such that the generation of a large amount of waste water in the traditional method is avoided, the reaction conditions are mild, the operation is easy, the reaction selectivity is good, the product purity is high, the advantages of safety and environmental protection are provided, and the method is suitable for the industrial requirements on environmental protection.