897940-94-2Relevant articles and documents
Highly enantioselective access to primary propargylamines: 4-Piperidinone as a convenient protecting group
Aschwanden, Patrick,Stephenson, Corey R. J.,Carreira, Erick M.
, p. 2437 - 2440 (2006)
We report a highly enantioselective, catalytic three-component coupling of aldehydes, alkynes, and 4-piperidone hydrochloride hydrate to afford the corresponding tertiary propargylamines in useful yields. The selective cleavage of the piperidone protectin